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About This Item
Empirical Formula (Hill Notation):
C14H12O3
CAS Number:
Molecular Weight:
228.24
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Product Name
Resveratrol, Vetec™, reagent grade, 98%
InChI
1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
SMILES string
Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2
InChI key
LUKBXSAWLPMMSZ-OWOJBTEDSA-N
grade
reagent grade
product line
Vetec™
assay
98%
form
powder
solubility
acetone: 50 mg/mL
storage temp.
−20°C
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Application
Selective inhibitor of COX−1.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
>392.0 °F - closed cup - (External MSDS)
flash_point_c
> 200.0 °C - closed cup - (External MSDS)
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Satya Dash et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(12), 2895-2901 (2013-09-28)
Overproduction of hepatic apolipoprotein B (apoB)-100 containing very low-density lipoprotein particles and intestinal apoB-48 containing chylomicrons contributes to hypertriglyceridemia seen in conditions such as obesity and insulin resistance. Some, but not all, preclinical and clinical studies have demonstrated that the
Timothy M Bass et al.
Mechanisms of ageing and development, 128(10), 546-552 (2007-09-19)
It was recently reported that the plant polyphenol resveratrol, found, e.g., in grape berry skins, extended lifespan in the fruit fly Drosophila melanogaster and the nematode worm Caenorhabditis elegans. This lifespan extension was dependent on an NAD(+)-dependent histone deacetylase, Sir2
Alexandra Maier-Salamon et al.
Annals of the New York Academy of Sciences, 1290, 98-106 (2013-07-17)
Resveratrol exhibits a variety of biological and pharmacological activities despite its extensive metabolism to sulfates and glucuronides in the intestine and liver. The metabolism of resveratrol is cell specific and strongly correlates with enzyme expression levels. However, a high rate
Morten Møller Poulsen et al.
Annals of the New York Academy of Sciences, 1290, 74-82 (2013-07-17)
In the search for novel preventive and therapeutic modalities in the management of metabolic diseases and obesity, resveratrol has attracted great attention over the past decades. Preclinical trials suggest that resveratrol mimics the metabolic effects of calorie restriction (CR) via
Silvie Timmers et al.
Annals of the New York Academy of Sciences, 1290, 83-89 (2013-07-17)
The number of people suffering from metabolic disorders is dramatically increasing worldwide. The need for new therapeutic strategies to combat this growing epidemic of metabolic diseases is therefore also increasing. In 2003, resveratrol was discovered to be a small molecule
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