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V900456

L-Glutathione reduced

Name: <SC>L</SC>-Glutathione reduced
Brand: VETEC

≥98%, Vetec^™

Synonym(s):

γ-L-Glutamyl-L-cysteinyl-glycine, GSH

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About This Item

Linear Formula:

H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H

CAS Number:

70-18-8

Molecular Weight:

307.32

UNSPSC Code:

12352209

PubChem Substance ID:

329829857

EC Number:

200-725-4

Beilstein/REAXYS Number:

1729812

MDL number:

MFCD00065939

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Properties

Product Name

L-Glutathione reduced, Vetec^™, reagent grade, ≥98%

grade

reagent grade

product line

Vetec^™

assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

mp

192-195 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChI key

RWSXRVCMGQZWBV-WDSKDSINSA-N

Description

Application

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Biochem/physiol Actions

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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