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V900480

CHAPS

Name: CHAPS
Brand: VETEC

Vetec^™, reagent grade, 96%

Synonym(s):

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

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About This Item

Empirical Formula (Hill Notation):

C₃₂H₅₈N₂O₇S

CAS Number:

75621-03-3

Molecular Weight:

614.88

UNSPSC Code:

12161703

PubChem Substance ID:

329829881

MDL number:

MFCD00012116

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grade

reagent grade

description

zwitterionic

product line

Vetec^™

assay

96%

form

powder

mol wt

micellar avg mol wt 6150

aggregation number

technique(s)

electrophoresis: suitable

CMC

6 mM (20-25°C)

mp

157 °C

transition temp

cloud point >100 °C

solubility

water: 10 g/L at 20 °C

application(s)

clinical research

SMILES string

C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22?,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChI key

UMCMPZBLKLEWAF-RFCNGIAKSA-N

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Application

CHAPS is a nondenaturing zwitterionic detergent for membrane biochemistry.
Useful for solubilizing membrane proteins and breaking protein-protein interactions. CHAPS′ small micellar molecular weight (6,150) and high critical micelle concentration (6-10 mM) allow it to be removed from samples by dialysis. It is also suitable for protein solubilization for isoelectric focusing and two-dimensional electrophoresis. CHAPS is commonly used for non-denaturing (without urea) IEF and has been shown to give excellent resolution of some subcellular preparations and plant proteins. Concentrations between 2-4% (w/v) are typically used in an IEF gel.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H360D

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Global Trade Item Number

SKU	GTIN
V900480-5G	04061835550616
V900480-1G	04061826759455

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