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About This Item
Linear Formula:
(CH3)2C=NOH
CAS Number:
Molecular Weight:
73.09
EC Number:
204-820-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1560146
MDL number:
Assay:
98%
Product Name
Acetone oxime, Vetec™, reagent grade, 98%
InChI key
PXAJQJMDEXJWFB-UHFFFAOYSA-N
InChI
1S/C3H7NO/c1-3(2)4-5/h5H,1-2H3
SMILES string
C\C(C)=N/O
grade
reagent grade
product line
Vetec™
assay
98%
bp
135 °C (lit.)
mp
60-63 °C (lit.)
density
0.901 g/mL at 25 °C (lit.)
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Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Flam. Sol. 2 - Skin Sens. 1B
Storage Class
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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M Rysková et al.
Folia biologica, 43(1), 19-24 (1997-01-01)
The genotoxic effects of N-nitroso-N-methylurea (MNU) and acetone oxime (ACOX) were tested in the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. We have performed the same assay on transgenic flies expressing the human gene encoding a glutathione S-transferase
C Kohl et al.
Carcinogenesis, 13(7), 1091-1094 (1992-07-01)
The hepatocarcinogenicity of acetoxime has been tentatively linked with its metabolic oxidation to the potent genotoxicant and carcinogen propane 2-nitronate (P2-N). In order to test the hypothesis that acetoxime is metabolized to P2-N, the oxime (20 mM) was incubated with
S S Mirvish et al.
Journal of the National Cancer Institute, 69(4), 961-962 (1982-10-01)
Acetoxime was tested for carcinogenicity by chronic administration in the drinking water to male and female outbred MRC-Wistar rats. The dose of 1.0 g/liter was administered 5 days/week for 18 months (total dose, 6.2--7.0 g/rat). The test compound induced benign
Stefanie Zorbas-Seifried et al.
Molecular pharmacology, 71(1), 357-365 (2006-10-20)
The presence of cis-configured exchangeable ligands has long been considered a prerequisite for antitumor activity of platinum complexes, but over the past few years, several examples violating this structure-activity relationship have been recognized. We report here on studies with the
N Guo et al.
Carcinogenesis, 11(9), 1659-1662 (1990-09-01)
The hepatocarcinogens 2-nitropropane and acetoxime have previously been found to induce a specific and qualitatively identical pattern of base damage in rat liver DNA and RNA, including the induction of increased levels of 8-hydroxyguanine. Because both 2-nitropropane and acetoxime are
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