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TLR9

toll-like receptor 9

别名:
CD289
物种:
UniProtKB ID:
基因ID:
  • Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • Mouse(81897) toll-like receptor 9
  • Rat(338457) toll-like receptor 9
  • naked mole-rat(101715478) toll-like receptor 9
  • cow(282602) toll-like receptor 9
  • Horse(100009693) toll-like receptor 9
  • sheep(494547) toll-like receptor 9
  • dog(403502) toll-like receptor 9
  • Zebrafish(403128) toll-like receptor 9
  • domestic cat(493839) toll-like receptor 9
  • Goat(100860819) toll-like receptor 9

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Small Molecule - Antagonist

Product Number
说明
物种
羟氯喹 硫酸酯, ≥98% (HPLC), powder,
物种
human
硫酸羟氯喹, United States Pharmacopeia (USP) Reference Standard,
物种
human
羟氯喹, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
物种
human
硫酸羟氯喹, analytical standard,
物种
human

Antibodies

Product Number
说明
物种反应性
应用
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-TLR9 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
ANTI-TLR9 antibody produced in mouse, clone 2H5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-TLR9/CD289 Antibody, clone 2L12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse, primate
应用
affinity binding assay
flow cytometry

immunohistochemistry

western blot

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting human TLR9, RP11-330H6.5,
物种
human
MISSION® esiRNA, targeting human TWF2, RP11-330H6.5,
物种
human