100013
4,4′-双甲氧基三苯甲基氯
95%
别名:
DMT-Cl
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关于此项目
线性分子式:
C6H5C(C6H4OCH3)2Cl
CAS Number:
分子量:
338.83
Beilstein:
2471942
EC 号:
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
95%
表单
solid
mp
119-123 °C (lit.)
官能团
chloro
phenyl
SMILES字符串
COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
InChI
1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
InChI key
JBWYRBLDOOOJEU-UHFFFAOYSA-N
一般描述
DMT-Cl常被用作有机合成中各种官能团的保护基团。
应用
用于核苷和核苷酸的羟基保护基团。
警示用语：
Danger
危险分类
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
储存分类代码
8B - Non-combustible corrosive hazardous materials
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
Journal of the American Chemical Society, 115, 4985-4985 (1993)
T Tuschl et al.
Biochemistry, 32(43), 11658-11668 (1993-11-02)
The three guanosines of the central core of a hammerhead ribozyme were replaced by 2-aminopurine ribonucleoside, xanthosine, isoguanosine, inosine, and deoxyguanosine. These analogues were incorporated by automated solid-phase synthesis, with the exception of isoguanosine. This was introduced by ligating a
Y Ueno et al.
Nucleic acids research, 21(19), 4451-4457 (1993-09-25)
The preparation of a nucleotidyl-peptide having a thymidine-5'-yl-(P-O)-serine phosphodiester bond, [H-Ala-Ser(pTpT)-Phe-OH](24) is described. After condensation between the phosphorylated peptide component and an oligonucleotide component, all protecting groups could be removed under neutral conditions without beta-elimination of the pTpT from the
Thomas F Scott et al.
Clinical neurology and neurosurgery, 127, 86-92 (2014-12-03)
To describe a "new natural history" of multiple sclerosis (MS), characterizing three patterns of progression in Relapsing MS (RMS) patients during the "treatment era," using newly developed definitions. By utilizing our simple model we intend to predict which patients are
Yuzhe Du et al.
Molecular pharmacology, 88(2), 273-280 (2015-05-15)
Voltage-gated sodium channels are the primary target of pyrethroid insecticides. Although it is well known that specific mutations in insect sodium channels confer knockdown resistance (kdr) to pyrethroids, the atomic mechanisms of pyrethroid-sodium channel interactions are not clearly understood. Previously
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