质量水平
方案
97%
mp
174-177 °C (lit.)
SMILES字符串
Nc1nccnn1
InChI
1S/C3H4N4/c4-3-5-1-2-6-7-3/h1-2H,(H2,4,5,7)
InChI key
MJIWQHRXSLOUJN-UHFFFAOYSA-N
一般描述
3-氨基-1,2,4-三嗪(ATN)用作单分子氮化碳前体，通过聚合反应制备高氮含量的介孔氮化碳。还用于合成有机金属复合物。
应用
- 药物应用中的抗肿瘤活性：一项研究报道了作为PDK1抑制剂的一系列新型3-氨基-1,2,4-三氮唑衍生物的开发， 这些衍生物对胰腺导管腺癌有显著的抗肿瘤活性，这显示了其在肿瘤治疗中的潜力 （Carbone et al., 2023）。
- 结晶学结构分析：该研究详细描述了一种涉及3-氨基-1,2,4-三氮唑的复合物的晶体结构和 Hirshfeld表面分析，提供了有关材料科学和配位化学领域分子相互作用和潜在应用的见解（Sangeetha et al., 2018）。
- NMR技术中的催化应用：研究中使用3-氨基-1,2,4-三氮唑，通过SABRE技术实现了水中NMR的显著极化，表明了其在改善NMR灵敏度的作用及其在磁共振成像的用途 （Zeng et al., 2014）。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Selective sensing performance of mesoporous carbon nitride with a highly ordered porous structure prepared from 3-amino-1, 2, 4-triazine
Mane GP, et al.
Journal of Materials Chemistry, 8, 2913-2920 (2013)
Grant Abernethy et al.
Journal of chromatography. A, 1285, 165-167 (2013-03-12)
A rapid liquid chromatography-mass spectrometry method to detect 3-amino-1,2,4-triazine (ATZ) in milk was developed as part of a programme to set up methods for detecting the economically motivated adulteration of raw milk with nitrogen-containing compounds. When ATZ was added to
Copper (II) complexes of 3-amino-1, 2, 4-triazine and 2-aminopyrazine: Strategies for designing crystalline materials using coordination polymers
Li L, et al.
Inorganica chimica acta, 362, 3845-3852 (2009)
Jirí Hanusek et al.
Organic & biomolecular chemistry, 5(3), 478-484 (2007-01-26)
Contrary to a previous report, the sulfurisation of phosphorus(III) derivatives by 3-amino-1,2,4-dithiazole-5-thione (xanthane hydride) does not yield carbon disulfide and cyanamide as the additional reaction products. The reaction of xanthane hydride with triphenyl phosphine or trimethyl phosphite yields triphenyl phosphine
J Kolls et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 205(3), 220-229 (1994-03-01)
Nitric oxide is believed to participate in nonspecific cellular immunity. Gram negative bacterial endotoxins increase the production of reactive nitrogen intermediates (RNI) in phagocytic cells by inducing the enzyme nitric oxide synthase II (NOS II). Anti-inflammatory glucocorticoids attenuate endotoxin-induced increases
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