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Merck
CN

103543

4-硝基苯甲醚

97%

别名:

1-甲氧基-4-硝基苯

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关于此项目

线性分子式:
O2NC6H4OCH3
化学文摘社编号:
分子量:
153.14
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
39032065
UNSPSC Code:
12352100
EC Number:
202-825-3
MDL number:
Beilstein/REAXYS Number:
1865361
Assay:
97%
Form:
solid
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assay

97%

form

solid

density

1.233 g/mL at 25 °C (lit.)

functional group

nitro

SMILES string

COc1ccc(cc1)[N+]([O-])=O

InChI

1S/C7H7NO3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3

InChI key

BNUHAJGCKIQFGE-UHFFFAOYSA-N

General description

4-硝基苯甲醚可经过氢氧根离子光化学亲核芳香取代,形成4-甲氧基苯酚和4-硝基苯酚

Application

使用4-硝基苯甲醚作为探针以确定 Kamlet-Taft溶剂参数Π*,以及在16-420°C温度范围内的高压和超临界水。 4-硝基苯甲醚被用作碳和能量补充剂,以用于分离 红球菌

Biochem/physiol Actions

4-硝基苯甲醚可被人肝脏微粒体经 O-去甲基化为4-硝基苯酚


pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Aquatic Chronic 3 - Carc. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

266.0 °F - closed cup

flash_point_c

130 °C - closed cup

ppe

Eyeshields, Gloves

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

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H V Gelboin et al.
Chemical research in toxicology, 9(6), 1023-1030 (1996-09-01)
A panel of 17 hybridomas producing (MAbs) against human cytochrome P450 2E1 (h2E1) was generated by immunizing mice with baculovirus-expressed h2E1. All 17 hybridoma clones gave positive ELISA or immunoblots with either baculovirus-or vaccinia virus-expressed h2E1. Two of the latter
H V Gelboin et al.
Biochemical pharmacology, 50(11), 1841-1850 (1995-11-27)
Cytochromes P450 3A3/4 are inordinately important P450 enzymes catalyzing the metabolism of a large variety of clinically useful drugs, steroids, and carcinogens. Two monoclonal antibodies, MAb 3-29-9 and MAb 275-1-2, were prepared to human P450 3A4 from mice immunized with
V V Shumyantseva et al.
Biochemistry and molecular biology international, 45(1), 171-179 (1998-06-23)
Semisynthetic flavocytochromes, obtained by covalent binding of riboflavin with cytochromes P450 2B4, were able to catalyze the H2O2-mediated reactions of aniline p-hydroxylation, aminopyrine N-demethylation and p-nitroanizole' O-dealkylation. The rates of the flavocytochrome-catalyzed, H2O2-supported reactions far exceeded those of the appropriate



全球贸易项目编号

货号GTIN
103543-25G04061838670601
103543-5G04061838670618