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Merck
CN

104051

吡啶酰胺

98%

别名:

2-吡啶甲酰胺

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关于此项目

经验公式(希尔记法):
C6H6N2O
化学文摘社编号:
分子量:
122.12
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
215-921-5
MDL number:
Assay:
98%
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产品名称

吡啶酰胺, 98%

InChI key

IBBMAWULFFBRKK-UHFFFAOYSA-N

InChI

1S/C6H6N2O/c7-6(9)5-3-1-2-4-8-5/h1-4H,(H2,7,9)

SMILES string

NC(=O)c1ccccn1

assay

98%

mp

110 °C (dec.) (lit.)

functional group

amide

Quality Level

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Application

以吡啶酰胺为模板制备分子印迹聚合物 。在一项研究中,吡啶酰胺被用于评估吡啶酰胺从HClO 4 中的铬(III) - 吡啶酰胺络合物中释放的动力学和机理。

Biochem/physiol Actions

吡啶酰胺是大鼠胰岛细胞核多聚(ADP-核糖)合成酶的潜在抑制剂 。吡啶酰胺充当二齿配体并与镧系元素硝酸盐,硫氰酸盐和高氯酸盐形成配合物

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bambang Kuswandi et al.
Analytica chimica acta, 591(2), 208-213 (2007-05-08)
A disposable ion-selective optode for mercury based on trityl-picolinamide (T-Pico) as neutral ionophore was developed. The sensing layer consist of plasticised PVC incorporating T-Pico as a selective ionophore for Hg2+, ETH 5418 as a chromoionophore, and potassium tetrakis[3,5-bis(trifluoromethyl)phenyl] borate as
Jeremy L Yap et al.
Organic & biomolecular chemistry, 10(15), 2928-2933 (2012-03-08)
By conducting a structure-activity relationship study of the backbone of a series of oligoamide-foldamer-based α-helix mimetics of the Bak BH3 helix, we have identified especially potent inhibitors of Bcl-x(L). The most potent compound has a K(i) value of 94 nM
Ryan A Olsen et al.
Journal of the American Chemical Society, 125(33), 10125-10132 (2003-08-14)
Pyridine carboxamides are a class of medicinal agents with activity that includes the reduction of iron-induced renal damage, the regulation of nicotinamidase activity, and radio- and chemosensitization. Such pharmacological activities, and the prevalence of the carboxamide moiety and the importance
Hongguang Liu et al.
Journal of medicinal chemistry, 56(3), 895-901 (2013-01-11)
Melanoma is an aggressive skin cancer with worldwide increasing incidence. Development of positron emission tomography (PET) probes for early detection of melanoma is critical for improving the survival rate of melanoma patients. In this research, (18)F-picolinamide-based PET probes were prepared
T Kawabata et al.
Acta pathologica japonica, 42(7), 469-475 (1992-07-01)
The effects of three isomers of pyridinecarboxamide (picolinamide (2-pyridinecarboxamide), nicotinamide (3-pyridinecarboxamide) and isonicotinamide (4-pyridinecarboxamide)) on iron-induced renal damage were studied. Pyridinecarboxamide (250 mg/kg body weight, ip) was administered 10 min before injection of ferric nitrilotriacetate (Fe(III)-NTA) (7.5 mgFe/kg body weight

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