方案
98%
mp
110 °C (dec.) (lit.)
官能团
amide
SMILES字符串
NC(=O)c1ccccn1
InChI
1S/C6H6N2O/c7-6(9)5-3-1-2-4-8-5/h1-4H,(H2,7,9)
InChI key
IBBMAWULFFBRKK-UHFFFAOYSA-N
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应用
以吡啶酰胺为模板制备分子印迹聚合物 。在一项研究中，吡啶酰胺被用于评估吡啶酰胺从HClO 4 中的铬（III） - 吡啶酰胺络合物中释放的动力学和机理。
生化/生理作用
吡啶酰胺是大鼠胰岛细胞核多聚（ADP-核糖）合成酶的潜在抑制剂 。吡啶酰胺充当二齿配体并与镧系元素硝酸盐，硫氰酸盐和高氯酸盐形成配合物。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Jeremy L Yap et al.
Organic & biomolecular chemistry, 10(15), 2928-2933 (2012-03-08)
By conducting a structure-activity relationship study of the backbone of a series of oligoamide-foldamer-based α-helix mimetics of the Bak BH3 helix, we have identified especially potent inhibitors of Bcl-x(L). The most potent compound has a K(i) value of 94 nM
Bambang Kuswandi et al.
Analytica chimica acta, 591(2), 208-213 (2007-05-08)
A disposable ion-selective optode for mercury based on trityl-picolinamide (T-Pico) as neutral ionophore was developed. The sensing layer consist of plasticised PVC incorporating T-Pico as a selective ionophore for Hg2+, ETH 5418 as a chromoionophore, and potassium tetrakis[3,5-bis(trifluoromethyl)phenyl] borate as
John N Zvimba et al.
Journal of inorganic biochemistry, 101(8), 1120-1128 (2007-06-15)
The protonation equilibria of a pentadentate ligand, N,N'-(2,2'-azanediylbis(ethane-2,1-diyl))dipicolinamide ([H(2)(5555)-N]) and the complexation of this ligand with Cu(II) Ca(II), Zn(II) and Ni(II) have been studied by pH-potentiometry, (1)H NMR spectroscopy and UV-vis spectrophotometry. (1)H NMR detected the protonation of the pyridyl
New chromium (III)-picolinamide complexes. Kinetics and mechanism of picolinamide liberation in HClO4 solutions.
Pazderska-Szablowicz M, et al.
Transition Met. Chem. (London), 31(8), 1075-1080 (2006)
T Yamagami et al.
Cancer research, 45(4), 1845-1849 (1985-04-01)
Streptozotocin and alloxan were administered to Wistar rats in combination with poly(adenosine diphosphate ribose) synthetase inhibitors. Ten to 16 months after the injection of streptozotocin (50 mg/kg body weight i.v.) and 3-aminobenzamide (345 mg/kg i.v.), streptozotocin (50 mg/kg) and nicotinamide
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