106615
2,2-双(羟甲基)丙酸
98%
别名:
Bis-MPA, DMPA®, 二羟甲基丙酸
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关于此项目
线性分子式:
(HOCH2)2C(CH3)COOH
化学文摘社编号:
分子量:
134.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-306-3
Beilstein/REAXYS Number:
1756385
MDL number:
Assay:
98%
Form:
solid
InChI key
PTBDIHRZYDMNKB-UHFFFAOYSA-N
InChI
1S/C5H10O4/c1-5(2-6,3-7)4(8)9/h6-7H,2-3H2,1H3,(H,8,9)
SMILES string
CC(CO)(CO)C(O)=O
vapor density
<1 (vs air)
assay
98%
form
solid
mp
189-191 °C (lit.)
solubility
H2O: soluble, acetone: slightly soluble, benzene: insoluble, methanol: soluble
functional group
carboxylic acid, hydroxyl
Quality Level
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Application
2,2-双(羟甲基)丙酸用于聚甲基硅氧烷（Si-PUD）改性聚氨酯分散体的合成和表征研究及其与粘土结合的纳米复合材料。2,2-双(羟甲基)丙酸基树枝状大分子在作为顺铂和多柔比星等强效抗癌药物的递送系统以及硼中子俘获疗法和光动力疗法的药剂方面具有很大的应用价值。
2,2-双(羟甲基)丙酸通常用作AB2 单体，用于合成超支化（hb）聚合物和树枝状大分子。
以2,2-双(羟甲基)丙酸合成了具有48个羟基的第四代三分枝树枝状大分子。
该酸简单衍生后就可通过“点击”叠氮-炔环加成反应来构建树枝状结构。
Legal Information
DMPA is a registered trademark of GEO Specialty Chemicals, Inc.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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A homologous series of hyperbranched polyesters (HBPEs) was successfully synthesized via an esterification reaction of 2,2-bis(methylol)propionic acid (bis-MPA) with pentaerythritol. The molecular weights of the HBPEs were 2160, 2660, 4150 and 5840 g/mol, respectively. These HBPEs were used as additives
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Cationic aliphatic polycarbonates bearing primary ammonium side chains have been developed with relatively high molecular weights and controlled macromolecular architectures. These polycarbonates exhibit reasonable antimicrobial activity against Gram-negative and Gram-positive bacteria. The prepared homopolymers could be effective against Gram-negative bacteria
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