108448
氰基乙酰胺
99%
别名:
2-Cyanoacetamide
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线性分子式:
NCCH2CONH2
化学文摘社编号:
分子量:
84.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-531-8
Beilstein/REAXYS Number:
878221
MDL number:
InChI key
DGJMPUGMZIKDRO-UHFFFAOYSA-N
InChI
1S/C3H4N2O/c4-2-1-3(5)6/h1H2,(H2,5,6)
SMILES string
NC(=O)CC#N
assay
99%
Quality Level
solubility
cold water: soluble 1gm in 6.5ml
functional group
amide, nitrile
General description
氰乙酰胺是合成维生素B6的起始试剂。它与硼酸缓冲液中的还原性碳水化合物反应，产生强烈的荧光，可用于碳水化合物作为硼酸盐络合物的自动分析。
氰乙酰胺是一种高度反应性化合物，常用作缩合和取代反应中的反应中间体。
氰乙酰胺是一种高度反应性化合物，常用作缩合和取代反应中的反应中间体。
Application
氰基乙酰胺可用于荧光分光光度法对一些抗组胺H1受体拮抗剂药物进行测定，例如依巴斯汀、二盐酸西替利嗪、以及盐酸非索非那定。它可用于3,4-二羟基苯丙氨酸的荧光测定。它可用作兔血清中壳聚糖酯的生物分析和药代动力学的柱后荧光衍生剂。。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
419.0 °F - closed cup
flash_point_c
215 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Cyanoacetamide derivatives as synthons in heterocyclic synthesis
Fadda, et al.
Turkish Journal of Chemistry, 32, 259-286 (2008)
Fluorometric determination of 3, 4-dihydroxyphenylalanine with 2-cyanoacetamide.
Liu Y, et al.
Journal of Fluorescence, 13(2), 123-128 (2003)
Fluorimetric determination of reducing carbohydrates with 2-cyanoacetamide and application to automated analysis of carbohydrates as borate complexes.
Honda S, et al.
Analytical Chemistry, 52(7), 1079-1082 (1980)
Hao Chen et al.
Scientific reports, 8(1), 13433-13433 (2018-09-09)
Early damage to transplanted organs initiates excess inflammation that can cause ongoing injury, a leading cause for late graft loss. The endothelial glycocalyx modulates immune reactions and chemokine-mediated haptotaxis, potentially driving graft loss. In prior work, conditional deficiency of the
Cyanoacetamide derivatives as synthons in heterocyclic synthesis.
Fadda AA, et al.
Turkish Journal of Chemistry, 32(3), 259-286 (2008)
商品
Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.
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