109509
2-氯苯肼 盐酸盐
97%
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关于此项目
线性分子式:
ClC6H4NHNH2·HCl
化学文摘社编号:
分子量:
179.05
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
255-194-1
Beilstein/REAXYS Number:
3699381
MDL number:
Assay:
97%
InChI key
ADODRSVGNHNKAT-UHFFFAOYSA-N
InChI
1S/C6H7ClN2.ClH/c7-5-3-1-2-4-6(5)9-8;/h1-4,9H,8H2;1H
SMILES string
Cl.NNc1ccccc1Cl
assay
97%
mp
200-203 °C (dec.) (lit.)
Application
2-Chlorophenylhydrazine hydrochloride was used to study intrinsic resistance of Mycobacterium smegmatis to fluoroquinolones, used for treatment of Mycobacterium tuberculosis. It may be used in pyrazoline synthesis.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Mohammad Abdel-Halim et al.
Bioorganic & medicinal chemistry, 21(23), 7343-7356 (2013-10-22)
Derivatives with scaffolds of 1,3,5-tri-substituted pyrazoline and 1,3,4,5-tetra-substituted pyrazoline were synthesized and tested for their inhibitory effects versus the p53(+/+) HCT116 and p53(-/-) H1299 human tumor cell lines. Several compounds were active against the two cell lines displaying IC50 values
C Montero et al.
Antimicrobial agents and chemotherapy, 45(12), 3387-3392 (2001-11-16)
The fluoroquinolones (FQ) are used in the treatment of Mycobacterium tuberculosis, but the development of resistance could limit their effectiveness. FQ resistance (FQ(R)) is a multistep process involving alterations in the type II topoisomerases and perhaps in the regulation of
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