112976
2,5-二叔丁基氢醌
99%
别名:
1,4-二羟基-2,5-二叔丁基苯, 2,5-二叔丁基-1,4-二羟基苯, 2,5-二叔丁基-1,4-苯二醇, 2,5-二叔丁基-1,4-苯氢醌, 2,5-二叔丁基喹啉, 2,5-二羟基-1,4-二叔丁基苯, 2,5-双(1,1-二甲基乙基)-1,4-苯二醇, 3,6-二叔丁基对苯二酚
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关于此项目
线性分子式:
[(CH3)3C]2C6H2-1,4-(OH)2
化学文摘社编号:
分子量:
222.32
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-841-8
Beilstein/REAXYS Number:
2049542
MDL number:
Assay:
99%
Form:
solid
产品名称
2,5-二叔丁基氢醌, 99%
InChI key
JZODKRWQWUWGCD-UHFFFAOYSA-N
InChI
1S/C14H22O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8,15-16H,1-6H3
SMILES string
CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C
assay
99%
form
solid
autoignition temp.
790 °F
mp
216-218 °C (lit.)
Quality Level
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Application
2,5-二叔丁基对苯二酚是用于测量铜（II）酶样催化剂催化活性的氧化底物。
Biochem/physiol Actions
2,5-二叔丁基对苯二酚可特异性抑制大鼠心室肌浆网（SR）的Ca2+摄取。
阻断人体 β 细胞的钙依赖性胰岛素信号
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A A Kabbara et al.
The American journal of physiology, 272(2 Pt 2), H1001-H1010 (1997-02-01)
The effects of 2,5-di-tert-butylhydroquinone (TBQ) on cardiac muscle contractility were investigated using cardiac preparations from the right ventricle of the rat. In saponin-skinned preparations, TBQ (50 and 100 microM) did not significantly affect the maximal isometric Ca2+-activated force or the
Salvatore Nesci et al.
Biochimie, 140, 73-81 (2017-06-28)
The mitochondrial F-ATPase can be activated either by the classical cofactor Mg
Francesco Tadini-Buoninsegni et al.
Molecular pharmacology, 73(4), 1134-1140 (2008-01-24)
The inhibitory effects of thapsigargin, cyclopiazonic acid, and 2,5-di(tert-butyl)hydroquinone, and 1,3-dibromo-2,4,6-tri(methylisothiouronium)benzene on the Ca(2+) ATPase were characterized by comparative measurements of sequential reactions of the catalytic and transport cycle, including biochemical measurements and detection of charge movements within a single
Pedro C Redondo et al.
Biochimica et biophysica acta, 1783(6), 1163-1176 (2008-01-15)
Endogenously expressed human canonical transient receptor potential 1 (hTRPC1) and human canonical transient receptor potential 6 (hTRPC6) have been shown to play a role in store-operated Ca2+ entry (SOCE) in human platelets, where two mechanisms for SOCE, regulated by the
W A Macdonald et al.
The Journal of physiology, 573(Pt 1), 187-198 (2006-03-25)
Slow-twitch mechanically skinned fibres from rat soleus muscle were bathed in solutions mimicking the myoplasmic environment but containing different [ADP] (0.1 microm to 1.0 mm). The effect of ADP on sarcoplasmic reticulum (SR) Ca2+-content was determined from the magnitude of
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