114715
苯肼 盐酸盐
≥99%
别名:
Phenylhydrazinium chloride
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关于此项目
线性分子式:
C6H5NHNH2 · HCl
化学文摘社编号:
分子量:
144.60
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-444-7
Beilstein/REAXYS Number:
3594958
MDL number:
Assay:
≥99%
Form:
solid
Quality Level
assay
≥99%
form
solid
mp
250-254 °C (dec.) (lit.)
functional group
hydrazine
SMILES string
Cl[H].NNc1ccccc1
InChI
1S/C6H8N2.ClH/c7-8-6-4-2-1-3-5-6;/h1-5,8H,7H2;1H
InChI key
JOVOSQBPPZZESK-UHFFFAOYSA-N
Application
盐酸苯肼用于检测贫血小鼠 EPO 反应性正常成红细胞样细胞中 Janus 蛋白酪氨酸激酶 (JAK) 的酪氨酸磷酸化 。
Biochem/physiol Actions
将盐酸苯肼腹腔注射到野生型和 Hp、Hx 单缺失小鼠体内时，会引起急性溶血 ，从而会抑制动物组织切片中辣根过氧化物 (HRP) 残留活性 。
Preparation Note
50 g 盐酸苯肼溶于 1 mL 水中，得到澄清、淡黄色溶液。
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Clinton Stewart et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 22(1), 612-629 (2019-12-10)
Cyclophosphamide is widely used to treat children with medulloblastoma; however, little is known about its brain penetration. We performed cerebral microdialysis to characterize the brain penetration of cyclophosphamide (130 mg/kg, IP) and its metabolites [4-hydroxy-cyclophosphamide (4OH-CTX) and carboxyethylphosphoramide mustard (CEPM)]
Phenylhydrazine as inhibitor of horseradish peroxidase for use in immunoperoxidase procedures.
W Straus
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 20(11), 949-951 (1972-11-01)
Y Yamamura et al.
Molecular and cellular biology, 18(3), 1172-1180 (1998-03-06)
Abnormal erythropoietin (EPO)-independent cell growth is induced after infection of erythroid progenitor cells with a polycythemic strain of Friend virus (FVp). Binding of its Env-related glycoprotein (gp55) to the EPO receptor (EPOR) mimics the activation of the EPOR with EPO.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 114715-500G | 04061838702906 |
| 114715-100G | 04061835370153 |
| 114715-5G | 04061835370160 |