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115053

4-硝基苯乙基溴

Name: 4-硝基苯乙基溴
Brand: ALDRICH

98%

别名:

1-(2-溴乙基)-4-硝基苯, 2-(4-硝基苯基)乙基溴

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关于此项目

线性分子式:

O₂NC₆H₄CH₂CH₂Br

化学文摘社编号:

5339-26-4

分子量:

230.06

EC Number:

226-271-7

UNSPSC Code:

12352100

PubChem Substance ID:

24847197

Beilstein/REAXYS Number:

1909321

MDL number:

MFCD00007386

Assay:

98%

Form:

solid

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属性

assay

98%

form

solid

mp

67-69 °C (lit.)

functional group

bromo, nitro

SMILES string

[O-][N+](=O)c1ccc(CCBr)cc1

InChI

1S/C8H8BrNO2/c9-6-5-7-1-3-8(4-2-7)10(11)12/h1-4H,5-6H2

InChI key

NTURQZFFJDCTMZ-UHFFFAOYSA-N

说明

General description

4-nitrophenethyl bromide is an electrophile which accepts a lone pair of electrons from one of the nitrogen atoms in the polyazamacrocycle.

Application

4-nitrophenethyl bromide is used a s a GST T1-1 substrate for identifying many kinetic parameters (Km, Kcat) for hGST T1-1 variants.

Biochem/physiol Actions

4-Nitrophenethyl bromide is used as a marker in for the θ-class of glutathione S-transferases (GSTs). It activates the human θ-class glutathione transferase T1-1 enzyme.

pictograms

GHS07

signalword

Warning

hcodes

H315,H317,H319,H335

pcodes

P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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A glutathione S-transferase (GST) isozyme from broccoli with significant sequence homology to the mammalian theta-class of GSTs.

M F Lopez et al.

Biochimica et biophysica acta, 1205(1), 29-38 (1994-03-16)

A novel glutathione S-transferase (GST) was purified from broccoli (Brassica oleracea var. italica). Partial amino-acid sequencing indicated that the protein shared significant homology with several different plant GSTs from maize, silene, Dianthus, Nicotiana and Triticum, but little homology to yeast

Residue 234 in glutathione transferase T1-1 plays a pivotal role in the catalytic activity and the selectivity against alternative substrates.

Abeer Shokeer et al.

The Biochemical journal, 388(Pt 1), 387-392 (2005-02-03)

GST (glutathione transferase) T1-1 plays an important role in the biotransformation of halogenated alkanes, which are used in large quantities as solvents and occur as environmental pollutants. Many reactions that are catalysed by GST T1-1 qualify as detoxification processes, but

Characterization and physicochemical properties of a lipase from Pseudomonas mendocina 3121-1.

Birute Surinenaite et al.

Biotechnology and applied biochemistry, 36(Pt 1), 47-55 (2002-08-01)

The lipase from Pseudomonas mendocina 3121-1 was found to be homogeneous with a molecular mass of 30 kDa by SDS/PAGE. It is composed of two identical subunits. A molecular mass of 62 kDa was determined by gel chromatography on a

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货号	GTIN
115053-5G	04061838703057
115053-25G	04061832104928
115053-1G	04061821000002