115312
N-ω-甲基色胺
99%
别名:
2-(吲哚-3-基)-N-甲基乙胺, 3-(2-[甲氨基]乙基)吲哚, 3-(2-甲基氨基乙基)吲哚, N-单甲基色胺, N10-甲基色胺, 甲基色胺
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关于此项目
经验公式（希尔记法）:
C11H14N2
化学文摘社编号:
分子量:
174.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-507-9
MDL number:
Assay:
99%
Form:
solid
InChI key
NCIKQJBVUNUXLW-UHFFFAOYSA-N
InChI
1S/C11H14N2/c1-12-7-6-9-8-13-11-5-3-2-4-10(9)11/h2-5,8,12-13H,6-7H2,1H3
SMILES string
CNCCc1c[nH]c2ccccc12
assay
99%
form
solid
mp
87-89 °C (lit.)
functional group
amine
Quality Level
Application
N-ω-甲基色胺已用于制备N-乙酰基-α−甲基色胺。
N-ω-甲基色胺已用于通过钩藤(U. tomentosa)蛋白提取物生物合成dolichantoside。
作为反应物用于制备：
- Manzamine类似物用于控制神经炎症和脑部感染
- 血清素4受体(5-HT4)受体激动剂
- Glypetelotine，一种含硫的吲哚生物碱
- 周期蛋白依赖性激酶(CDK4)的选择性抑制剂
- 人速激肽NK-2受体拮抗剂
- 酪氨酸特异性蛋白激酶pp60c-src SH2结构域的抑制剂
Packaging
无底玻璃瓶。内含物装在锥底内插管中。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
R N Cory et al.
The Journal of pharmacology and experimental therapeutics, 236(1), 48-54 (1986-01-01)
The contractile response of the isolated rabbit aorta elicited by 5-hydroxytryptamine (5-HT) and five partial agonists acting on the 5-HT2 receptor were separated into a phasic and a tonic response by altering the [Ca++] in the buffer. A kinetic analysis
T Takahashi et al.
The International journal of applied radiation and isotopes, 36(12), 965-969 (1985-12-01)
Five indolealkylamines (N,N-dimethyltryptamine, N-methyltryptamine, bufotenine, O-methylbufotenine, N,N,N-trimethyltryptamine iodide) were labeled with 11C by use of 11CH3I. The labeled compounds were synthesized with a radiochemical yield of 2-50% (based on trapped 11CH3I) in 20-35 min with radiochemical purities of more than
W J VandenHeuvel et al.
Journal of chromatographic science, 21(3), 119-124 (1983-03-01)
This report focuses on recent applications of capillary column GLC to the analysis of drugs and metabolites, other xenobiotics, natural products, and environmental contaminants in samples of biological origin. The increasing use of selected ion monitoring, combined with stable isotope
R W Walker et al.
Journal of chromatography, 289, 223-229 (1984-04-27)
A capillary column gas-liquid chromatography selected ion monitoring-based method was developed for the measurement of [13C,15N]N-methyltryptamine ( NMT ) in human urine. The method was employed to establish the extent of conversion of [13C,15N]tryptamine to the correspondingly labeled NMT in
T J Williams et al.
European journal of pharmacology, 245(3), 197-201 (1993-05-15)
The binding of [3H]5-hydroxytryptamine (5-HT) to rat enteric membranes was inhibited by the inclusion of 5-HT 2-methyl-5-HT, 5-hydroxytryptophan, N,N,N-triethyltryptamine and 2-Br-N,N-diethyltryptamine in the incubation buffer. In contrast, tryptamine, 5-methoxytryptamine and 2-methyl-N,N-diethyltryptamine enhanced binding. Ascorbate and dithiothreitol facilitated and reduced binding
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