117455
对甲苯磺酰氟
98%
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线性分子式:
CH3C6H4SO2F
化学文摘社编号:
分子量:
174.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
207-238-6
MDL number:
Assay:
98%
Form:
solid
InChI key
IZZYABADQVQHLC-UHFFFAOYSA-N
InChI
1S/C7H7FO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3
SMILES string
Cc1ccc(cc1)S(F)(=O)=O
assay
98%
form
solid
reaction suitability
reaction type: click chemistry
bp
112 °C/16 mmHg (lit.)
mp
41-42 °C (lit.)
Quality Level
General description
p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.
Application
p-Toluenesulfonyl fluoride was used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.
Protease inhibitor.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
222.8 °F - closed cup
flash_point_c
106 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Tomonori Kaneko et al.
Protein science : a publication of the Protein Society, 14(2), 558-565 (2005-01-06)
Growth-limiting stresses in bacteria induce the general stress response to protect the cells against future stresses. Energy stress caused by starvation conditions in Bacillus subtilis is transmitted to the sigma(B) transcription factor by stress-response regulators. RsbP, a positive regulator, is
Tsuyoshi Fujita et al.
Cellular signalling, 17(2), 167-175 (2004-10-21)
In this study, we examined the mechanism by which CD38 cleavage is regulated through the mitogen-activated protein (MAP) kinases after stimulation by fMLP and interleukin-8 (IL-8) in neutrophils. Both fMLP and IL-8 increased chemotaxis and decreased CD38 protein in neutrophils
Nobuyuki Shibata et al.
FEMS microbiology letters, 256(1), 137-144 (2006-02-21)
Lipophilic Malassezia species may induce catheter-associated sepsis in premature neonates and immunocompromised patients receiving parenteral lipid emulsions. To assess the participation of lipolytic enzymes in the pathogenesis of this yeast, we cloned a gene encoding the enzyme. A lipolytic enzyme
Jinkui Yang et al.
Biotechnology letters, 27(15), 1123-1128 (2005-09-01)
Lecanicillium psalliotae produced an extracellular protease (Ver112) which was purified to apparent homogeneity giving a single band on SDS-PAGE with a molecular mass of 32 kDa. The optimum activity of Ver112 was at pH 10 and 70 degrees C (over
Toshihiro Takahashi et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 58(5), 557-566 (2003-05-09)
For preparing [18F]labeled compounds free from bromo-compounds for PET (positron emission tomography) studies, we propose the following two processes in which no separation is needed between the fluoro-compound and bromo-compound : (1). the bromo-compound is first converted into O-tosylate, which
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