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Merck
CN

119660

磷酸三(2-氯乙基)酯

97%

别名:

磷酸三(2-氯乙基)酯

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线性分子式:
(ClCH2CH2O)3P(O)
化学文摘社编号:
分子量:
285.49
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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蒸汽压

<10 mmHg ( 25 °C)

质量水平

方案

97%

折射率

n20/D 1.472 (lit.)

沸点

192 °C/10 mmHg (lit.)

溶解性

H2O: soluble 7.82 g/L

密度

1.39 g/mL at 25 °C (lit.)

SMILES字符串

ClCCOP(=O)(OCCCl)OCCCl

InChI

1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

InChI key

HQUQLFOMPYWACS-UHFFFAOYSA-N

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一般描述

磷酸三(2-氯乙基)酯在塑料中用作阻燃剂,尤其是在汽车和家具中使用的硬质泡沫以及用于建筑保温的硬质泡沫中

应用

通过固相微萃取装置使用三(2-氯乙基)磷酸酯对空气中的有机磷酸酯进行了动态采样

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

449.6 °F - closed cup

闪点(°C)

232 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H B Matthews et al.
Toxicology and industrial health, 6(1), 1-15 (1990-01-01)
Tris(2-chloroethyl)phosphate (TRCP), a flame-retardant plasticizer used in plastics, polymeric foams and synthetic fibers, was studied as part of the National Toxicology Program's class study of phosphate flame-retardants. TRCP was administered at 0, 22, 44, 88, 175 and 350 mg/kg to
Thorvald Staaf et al.
Journal of environmental monitoring : JEM, 7(9), 883-887 (2005-08-27)
In this study the occurrence of ten organophosphate triesters in indoor air at 29 different locations was investigated. They were detected at all locations and a total of ten compounds were identified. The predominant compounds were the chlorinated compounds tris(chloroisopropyl)
H B Matthews et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(4), 477-485 (1993-05-01)
Previous short-term studies of tris(2-chloroethyl)phosphate (TRCP), a flame retardant used in industrial and consumer products, demonstrated that repeated administration of 350 mg TRCP/kg body wt by oral gavage resulted in necrosis of pyramidal neurons in the CA1 region of the
H A Tilson et al.
Toxicology and applied pharmacology, 106(2), 254-269 (1990-11-01)
Adult female, Fischer-344 rats were exposed to 275 mg/kg of tris(2-chloroethyl)phosphate (TRCP) by gavage. TRCP produced consistent signs of convulsive activity within 60-90 min after dosing and extensive loss of CAT hippocampal pyramidal cells when examined 7 days after dosing.
L T Burka et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 443-447 (1991-03-01)
Tris(2-chloroethyl) phosphate (TRCP), a flame retardant, produces a dose-, sex-, and species-dependent lesion in the hippocampal region of the brain following subchronic oral administration. This lesion is more common and more severe in female F344 rats than in male F344

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