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119660

磷酸三(2-氯乙基)酯

Name: 磷酸三(2-氯乙基)酯
Brand: ALDRICH

97%

别名:

磷酸三（2-氯乙基）酯

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关于此项目

线性分子式:

(ClCH₂CH₂O)₃P(O)

化学文摘社编号:

115-96-8

分子量:

285.49

NACRES:

NA.22

PubChem Substance ID:

24847295

UNSPSC Code:

12352100

EC Number:

204-118-5

MDL number:

MFCD00000967

Assay:

97%

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属性

vapor pressure

<10 mmHg ( 25 °C)

assay

97%

refractive index

n20/D 1.472 (lit.)

bp

192 °C/10 mmHg (lit.)

solubility

H₂O: soluble 7.82 g/L

density

1.39 g/mL at 25 °C (lit.)

SMILES string

ClCCOP(=O)(OCCCl)OCCCl

InChI

1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

InChI key

HQUQLFOMPYWACS-UHFFFAOYSA-N

说明

General description

磷酸三（2-氯乙基）酯在塑料中用作阻燃剂，尤其是在汽车和家具中使用的硬质泡沫以及用于建筑保温的硬质泡沫中。

Application

通过固相微萃取装置使用三（2-氯乙基）磷酸酯对空气中的有机磷酸酯进行了动态采样。

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pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H351,H360

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

449.6 °F - closed cup

flash_point_c

232 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

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In vivo and in vitro biological effects of the flame retardants tris(2,3-dibromopropyl) phosphate and tris(2-chlorethyl)orthophosphate.

M Sala et al.

European journal of cancer & clinical oncology, 18(12), 1337-1344 (1982-12-01)

Tris(2,3-dibromopropyl)phosphate (Tris-BP) and Tris(2-chloroethyl) orthophosphate (Genomoll P) were analyzed for mutagenic and carcinogenic activity in several in vitro and in vivo mammalian systems. In the in vitro tests both Tris-BP and Genomoll P increased sister chromatid exchanges in V79 cells

Proapoptotic effect of a micropollutant (tris-(2-chloroethyl)-phosphate) at environmental level in primary cultured renal proximal tubule cells.

Xianghao Ren et al.

Journal of water and health, 10(4), 522-530 (2012-11-21)

Being a typical micropollutant, tris-(2-chloroethyl)-phosphate (TCEP) is often found in aquatic environments. However, the potential effects of TCEP at environmental concentrations on apoptotic mechanisms are mostly unknown. Thus, the purpose of this study is to investigate the apoptotic regulatory protein

Tris(2-chloroethyl) phosphate pharmacokinetics in the Fischer 344 rat: a comparison of conventional methods and in vivo microdialysis coupled with tandem mass spectrometry.

K Dix et al.

Journal of pharmaceutical sciences, 83(11), 1622-1629 (1994-11-01)

The pharmacokinetics of tris(2-chloroethyl) phosphate (TRCP, 20 mg/kg, iv) were investigated in awake male and female and anesthetized male Fischer 344 (F344) rats by conventional (CONV) sampling/detection methods (blood withdrawal with sample workup and analysis for TRCP). TRCP pharmacokinetics were

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全球贸易项目编号

货号	GTIN
119660-25G	04061838710369