119660
磷酸三(2-氯乙基)酯
97%
别名:
磷酸三（2-氯乙基）酯
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关于此项目
线性分子式:
(ClCH2CH2O)3P(O)
化学文摘社编号:
分子量:
285.49
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
204-118-5
MDL number:
Assay:
97%
产品名称
磷酸三(2-氯乙基)酯, 97%
InChI key
HQUQLFOMPYWACS-UHFFFAOYSA-N
InChI
1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2
SMILES string
ClCCOP(=O)(OCCCl)OCCCl
vapor pressure
<10 mmHg ( 25 °C)
assay
97%
refractive index
n20/D 1.472 (lit.)
bp
192 °C/10 mmHg (lit.)
solubility
H2O: soluble 7.82 g/L
density
1.39 g/mL at 25 °C (lit.)
Quality Level
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Application
通过固相微萃取装置使用三（2-氯乙基）磷酸酯对空气中的有机磷酸酯进行了动态采样。
General description
磷酸三（2-氯乙基）酯在塑料中用作阻燃剂，尤其是在汽车和家具中使用的硬质泡沫以及用于建筑保温的硬质泡沫中。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
449.6 °F - closed cup
flash_point_c
232 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
K Dix et al.
Journal of pharmaceutical sciences, 83(11), 1622-1629 (1994-11-01)
The pharmacokinetics of tris(2-chloroethyl) phosphate (TRCP, 20 mg/kg, iv) were investigated in awake male and female and anesthetized male Fischer 344 (F344) rats by conventional (CONV) sampling/detection methods (blood withdrawal with sample workup and analysis for TRCP). TRCP pharmacokinetics were
Xianghao Ren et al.
Journal of water and health, 10(4), 522-530 (2012-11-21)
Being a typical micropollutant, tris-(2-chloroethyl)-phosphate (TCEP) is often found in aquatic environments. However, the potential effects of TCEP at environmental concentrations on apoptotic mechanisms are mostly unknown. Thus, the purpose of this study is to investigate the apoptotic regulatory protein
M Sala et al.
European journal of cancer & clinical oncology, 18(12), 1337-1344 (1982-12-01)
Tris(2,3-dibromopropyl)phosphate (Tris-BP) and Tris(2-chloroethyl) orthophosphate (Genomoll P) were analyzed for mutagenic and carcinogenic activity in several in vitro and in vivo mammalian systems. In the in vitro tests both Tris-BP and Genomoll P increased sister chromatid exchanges in V79 cells
Jennifer Jackson et al.
The Science of the total environment, 405(1-3), 153-160 (2008-08-08)
Synthetic endocrine-disrupting chemicals (EDCs) have been found in surface waters throughout the United States, and are known to enter waterways via discharge from wastewater treatment plants (WWTPs). Studies addressing EDCs in wastewater do not examine their specific sources upstream of
H B Matthews et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 20(4), 477-485 (1993-05-01)
Previous short-term studies of tris(2-chloroethyl)phosphate (TRCP), a flame retardant used in industrial and consumer products, demonstrated that repeated administration of 350 mg TRCP/kg body wt by oral gavage resulted in necrosis of pyramidal neurons in the CA1 region of the
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