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122564

二氯甲基二乙胺盐酸盐

Name: 二氯甲基二乙胺 盐酸盐
Brand: ALDRICH

98%

别名:

2-氯-N-(2-氯乙基)-N-甲基乙胺, N-甲基双(2-氯乙基)胺盐酸盐, 二(2-氯乙基)甲基胺, 双(2-氯乙基)甲胺, 氮芥

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关于此项目

线性分子式:

(ClCH₂CH₂)₂NCH₃·HCl

化学文摘社编号:

55-86-7

分子量:

192.51

NACRES:

NA.22

PubChem Substance ID:

24847496

UNSPSC Code:

12352100

EC Number:

200-246-0

MDL number:

MFCD00012517

Assay:

98%

Form:

solid

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属性

Quality Level

100

assay

98%

form

solid

mp

108-111 °C (lit.)

solubility

H₂O: very soluble, alcohol: soluble

functional group

amine, chloro

SMILES string

Cl.CN(CCCl)CCCl

InChI

1S/C5H11Cl2N.ClH/c1-8(4-2-6)5-3-7;/h2-5H2,1H3;1H

InChI key

QZIQJVCYUQZDIR-UHFFFAOYSA-N

说明

Application

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

Biochem/physiol Actions

Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.

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pictograms

GHS06,GHS08,GHS05

signalword

Danger

hcodes

H300 + H310,H314,H340,H350,H360D

pcodes

P202 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Repr. 1B - Skin Corr. 1B

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Characterizing variants of unknown significance in rhodopsin: A functional genomics approach.

Aliete Wan et al.

Human mutation, 40(8), 1127-1144 (2019-04-13)

Characterizing the pathogenicity of DNA sequence variants of unknown significance (VUS) is a major bottleneck in human genetics, and is increasingly important in determining which patients with inherited retinal diseases could benefit from gene therapy. A library of 210 rhodopsin

MTA1 promotes the invasion and migration of oral squamous carcinoma by inducing epithelial-mesenchymal transition via the hedgehog signaling pathway.

Qingcui Song et al.

Experimental cell research, 382(1), 111450-111450 (2019-06-04)

The metastasis-associated gene 1 (MTA1) has previously been recognized as an oncogene in many tumors, and aberrant MTA1 expression has been related to invasion and migration; however, its role and underlying molecular mechanism in oral squamous carcinoma (OSCC) remain largely

Arginine vasotocin (AVT)/mesotocin (MT) receptors in chickens: Evidence for the possible involvement of AVT-AVPR1 signaling in the regulation of oviposition and pituitary prolactin expression.

Chao Wu et al.

General and comparative endocrinology, 281, 91-104 (2019-05-24)

Two structurally related peptides, arginine vasotocin (AVT) and mesotocin (MT), are reported to regulate many physiological processes, such as anti-diuresis and oviposition in birds, and their actions are likely mediated by four AVT/MT receptors (AVPR1A, AVPR1B, MTR and AVPR2b), which

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全球贸易项目编号

货号	GTIN
122564-25G	04061832105963
122564-5G	04061832105970

主要文件

二氯甲基二乙胺盐酸盐

98%