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Merck
CN

122564

Sigma-Aldrich

二氯甲基二乙胺 盐酸盐

98%

别名:

2-氯-N-(2-氯乙基)-N-甲基乙胺, N-甲基双(2-氯乙基)胺 盐酸盐, 二(2-氯乙基)甲基胺, 双(2-氯乙基)甲胺, 氮芥

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关于此项目

线性分子式:
(ClCH2CH2)2NCH3·HCl
化学文摘社编号:
分子量:
192.51
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

98%

表单

solid

mp

108-111 °C (lit.)

溶解性

H2O: very soluble
alcohol: soluble

官能团

amine
chloro

SMILES字符串

Cl.CN(CCCl)CCCl

InChI

1S/C5H11Cl2N.ClH/c1-8(4-2-6)5-3-7;/h2-5H2,1H3;1H

InChI key

QZIQJVCYUQZDIR-UHFFFAOYSA-N

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应用

Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.

生化/生理作用

Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.

警示用语:

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 2 Oral - Carc. 1B - Eye Dam. 1 - Muta. 1B - Repr. 1B - Skin Corr. 1B

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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U Wormser et al.
Archives of toxicology, 71(3), 165-170 (1997-01-01)
Mustard gas (sulphur mustard, SM) is a powerful vesicant employed as a chemical weapon. The present study demonstrates the effect of povidone iodine (PI) ointment against skin toxicity caused by SM. Gross and histopathological examinations showed that application of PI

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