123080
2-氨基-4-甲基吡啶
99%
别名:
2-氨基-4-甲基吡啶
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关于此项目
经验公式（希尔记法）:
C6H8N2
化学文摘社编号:
分子量:
108.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-780-9
Beilstein/REAXYS Number:
107066
MDL number:
Assay:
99%
InChI key
ORLGLBZRQYOWNA-UHFFFAOYSA-N
InChI
1S/C6H8N2/c1-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)
SMILES string
Cc1ccnc(N)c1
assay
99%
bp
230 °C (lit.)
Quality Level
Gene Information
human ... NOS1(4842), NOS2(4843), NOS3(4846)
rat ... Nos1(24598)
solubility
DMF: freely soluble, H2O: freely soluble, aliphatic hydrocarbons: slightly soluble, coal tar bases: freely soluble, lower alcohols: freely soluble, petroleum ether: slightly soluble
General description
2-氨基-4-甲基吡啶作为配体，形成甲氧基桥联的铜 (II) 配合物 。
Application
2-氨基-4-甲基吡啶用于合成 2-氨基-4-甲基吡啶-2-羟基苯甲酸盐 。
Biochem/physiol Actions
2-氨基-4-甲基吡啶抑制体外 小鼠 RAW 264.7 细胞分离的诱导型 NO 合成酶的活性 。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 2
flash_point_f
244.4 °F - closed cup
flash_point_c
118 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Synthesis, spectroscopic and magnetic properties of methoxo-bridged copper (II) complexes with 2-amino-4-methylpyridine as the ligand.
Komaei SA, et al.
Transition Metal Chemistry, 24(1), 104-107 (1999)
F Bergmann et al.
Archives internationales de pharmacodynamie et de therapie, 247(2), 275-282 (1980-10-01)
2-Amino-4-methylpyridine (2-AMP), when implanted into the ventral lateral thalamus of rats, does not cause stereotyped behavior. On the other hand, when compulsive biting and gnawing was evoked by thalamic implants of morphine (via stimulation of type 1 opiate receptors, which
M W Fryer et al.
General pharmacology, 29(4), 657-663 (1997-11-14)
1. The effects of 4-methyl-2-aminopyridine (4M2AP) and 4-aminopyridine (4AP) on spontaneous and evoked [3H]-noradrenaline overflow were compared in rabbit ear artery strips. The effects of 4M2AP on smooth muscle contractility were also investigated in isolated perfused ear arteries. 2. Both
W E Glover
European journal of pharmacology, 71(1), 21-31 (1981-04-24)
The effect of 4-aminopyridine (4AP) and 4-methyl-2-aminopyridine (4M2AP), 10(-3) M, was studied on isolated spontaneously beating right atria and electrically driven left atria of the rabbit and the cat. In the rabbit preparations, 4AP had a positive inotropic effect which
Madhukar Hemamalini et al.
Acta crystallographica. Section E, Structure reports online, 66(Pt 8), o2151-o2152 (2010-01-01)
The asymmetric unit of the title mol-ecular salt, C(6)H(9)N(2) (+)·C(7)H(5)O(3) (-), contains two cations and two anions. Both the salicylate anions contain an intra-molecular O-H⋯O hydrogen bond, which generates an S(6) ring. Both the 2-amino-4-methyl-pyridine mol-ecules are protonated at their
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