123463
1,2-环己二甲酸酐（主要为顺式异构体）
95%
别名:
六氢邻苯二甲酸酐
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关于此项目
经验公式（希尔记法）:
C8H10O3
化学文摘社编号:
分子量:
154.16
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
201-604-9
MDL number:
InChI key
MUTGBJKUEZFXGO-OLQVQODUSA-N
InChI
1S/C8H10O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h5-6H,1-4H2/t5-,6+
SMILES string
O=C1OC(=O)[C@H]2CCCC[C@@H]12
assay
95%
form
solid
bp
158 °C/17 mmHg (lit.)
mp
32-34 °C (lit.)
Quality Level
General description
顺式1,2-环己烷二羧酸酐（HHPA）是一种环状酸酐，可用于多种应用，例如：增塑剂、防锈剂和环氧树脂的固化剂。
Application
HPPA可以和三乙胺（TEA）一起用作制备聚酯树脂的聚合引发剂。它也可以用作固化1,4-丁二醇二缩水甘油醚的硬化剂，后者可用作电子设备的环氧体系。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Gunvor Johannesson et al.
Toxicology and applied pharmacology, 194(1), 69-78 (2004-01-20)
Hexahydrophthalic anhydride (HHPA), an industrially important chemical, is a highly allergenic compound. The aim of this work was to identify proteins in nasal lavage fluid (NLF) that form adducts with HHPA. Such bindings may induce production of specific immunoglobulin E
Gunvor A Johannesson et al.
Biomedical chromatography : BMC, 22(3), 327-332 (2007-10-17)
An immunoaffinity extraction (IAE) column was prepared for extraction of adducts between human serum albumin (HSA) and hexahydrophthalic anhydride (HHPA). HHPA is a strong sensitizer inducing immunoglobulin E antibodies in vivo. Polyclonal antibodies from a rabbit immunized with keyhole limpet
G Johannesson et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 31(7), 1021-1030 (2001-07-27)
Organic acid anhydrides (OAAs) are highly allergenic compounds used in the chemical industry. The OAAs probably act as haptens but the proteins that form conjugates with OAAs in vivo are still unknown. Conjugates between the anhydrides and serum albumins (SAs)
Isla Mickey et al.
The Histochemical journal, 34(10), 469-477 (2003-08-30)
In this study, we show the changes in the wall of the middle cerebral artery of a subject who suffered multiple system atrophy with autonomic failure. An electron-immunocytochemical approach was employed to reveal the presence of endothelin-1. Our results demonstrate
Leslie C Grammer et al.
Chest, 121(4), 1317-1322 (2002-04-12)
To determine whether the use of respiratory protective equipment would reduce the incidence of occupational asthma due to exposure to hexahydrophthalic anhydride (HHPA). Prospective cohort study. A facility that makes an epoxy resin product requiring HHPA for its manufacture. Sixty-six
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