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Merck
CN

12490

11H-苯并[a]芴

≥98.0%

别名:

1,2-苯并芴, 柯芴

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关于此项目

经验公式(希尔记法):
C17H12
化学文摘社编号:
分子量:
216.28
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-944-9
Beilstein/REAXYS Number:
2046363
MDL number:
Assay:
≥98.0%
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产品名称

11H-苯并[a]芴, ≥98.0%

InChI key

HKMTVMBEALTRRR-UHFFFAOYSA-N

InChI

1S/C17H12/c1-3-7-14-12(5-1)9-10-16-15-8-4-2-6-13(15)11-17(14)16/h1-10H,11H2

SMILES string

C1c2ccccc2-c3ccc4ccccc4c13

assay

≥98.0%

mp

185-190 °C

solubility

dioxane: soluble 0.1 g/10 mL, clear, colorless

Quality Level

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Application

11H-Benzo[a]fluorene has been used in a study on 7H-benzo[c]fluorine, major lung DNA adductor component in coal tar.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Radoslaw S Laufer et al.
Journal of the American Chemical Society, 124(9), 1854-1855 (2002-02-28)
Theoretical and chemical studies of the reactivity of isoprekinamycin, the kinamycins, and the lomaiviticins support the proposal that these natural products exhibit enhanced diazonium salt character and may owe their antitumor antibiotic properties to their ability to act as electrophilic
A Koganti et al.
Carcinogenesis, 21(8), 1601-1609 (2000-07-27)
Coal tar is a complex mixture that exhibits high carcinogenic potency in lungs of animals when administered in the diet. Studies have noted that lung tumor induction does not correlate with the benzo[a]pyrene content of coal tar, suggesting that other
Benzo[a]fluorene.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 32, 177-182 (1983-12-01)
C Atienza et al.
Organic letters, 3(2), 153-155 (2001-06-30)
[figure: see text] Thermal cyclization of 1-[2-(trimethylsilylethynyl)phenyl]-3-arylpropinones was expected to give benzo[b]fluorenones. However, benzo[a]-fluorenones were also formed as a result of a new rearrangement. These tetracycles possess the core structure of the fluostatins and isoprekinamycin.

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