Quality Segment
assay
95%
mp
160-162 °C (lit.)
functional group
chloro
storage temp.
−20°C
SMILES string
Clc1nnc(Cl)c2ccccc12
InChI
1S/C8H4Cl2N2/c9-7-5-3-1-2-4-6(5)8(10)12-11-7/h1-4H
InChI key
ODCNAEMHGMYADO-UHFFFAOYSA-N
Application
1,4-Dichlorophthalazine was used as starting reagent in the synthesis of series of 4-aryl-1-(4-methylpiperazin-1-yl)phthalazines. It was used as coupling reagent in the synthesis of novel soluble polymer-bound ligand. It was often used as building block in medicinal chemistry synthesis.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Matthew A J Duncton et al.
Bioorganic & medicinal chemistry letters, 16(6), 1579-1581 (2006-01-03)
A novel class of 1-(isoquinolin-5-yl)-4-arylamino-phthalazines is described as inhibitors of vascular endothelial growth factor receptor II (VEGFR-2). Many compounds display VEGFR-2 inhibitory activity with an IC(50) as low as 0.017 microM in an HTRF enzymatic assay. The compounds also inhibit
Synthesis of 4-aryl-1-(4-methylpiperazin-1-yl) phthalazines by Suzuki-type cross-coupling reaction.
Guery S, et al.
Synthesis, 2001(05), 699-701 (2001)
K De Wael et al.
Science & justice : journal of the Forensic Science Society, 55(6), 422-430 (2015-12-15)
Reactively-dyed black, navy blue and medium red cotton samples showing metamerism under fluorescent tube illumination were examined. Optical microscopy (bright field, polarization and fluorescence microscopy) was used, followed by microspectrometry in the visible range (MSP Vis), to differentiate the samples
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 126020-1G | 04061825752129 |
| 126020-5G | 04061832248707 |