Quality Level
assay
98%
form
powder
mp
191-193 °C (lit.)
SMILES string
Cc1cc2nc(-c3ccccn3)c(nc2cc1C)-c4ccccn4
InChI
1S/C20H16N4/c1-13-11-17-18(12-14(13)2)24-20(16-8-4-6-10-22-16)19(23-17)15-7-3-5-9-21-15/h3-12H,1-2H3
InChI key
NACXMBPTPBZQHY-UHFFFAOYSA-N
Application
6,7-Dimethyl-2,3-di-(2-pyridyl)quinoxaline has been used as an internal standard to investigate the clinical pharmacokinetics of nelfinavir mesylate, a potent inhibitor of HIV-1 protease.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
B Louveau et al.
Biomedical chromatography : BMC, 30(12), 2009-2015 (2016-06-10)
A precise and accurate high-performance liquid chromatography (HPLC) quantification method of rifampicin in human plasma was developed and validated using ultraviolet detection after an automatized solid-phase extraction. The method was validated with respect to selectivity, extraction recovery, linearity, intra- and
Salmaan Kanji et al.
Clinical pharmacokinetics, 59(3), 327-334 (2019-09-01)
Sustained low-efficiency dialysis (SLED) is a hybrid form of dialysis that is increasingly used in critically ill patients with kidney injury and hemodynamic instability. Antimicrobial dosing for patients receiving SLED is informed by pharmacokinetic studies that describe the drug clearance.
E Y Wu et al.
Journal of chromatography. B, Biomedical sciences and applications, 695(2), 373-380 (1997-08-01)
Nelfinavir mesylate, a potent and orally bioavailable inhibitor of HIV-1 protease (Ki=2 nM), has undergone Phase III clinical evaluation in a large population of HIV-positive patients. A high-performance liquid chromatography analytical method was developed to determine the pharmacokinetic parameters of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 126462-5G | 04061833320150 |