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Merck
CN

127221

2-二吡啶基酮

99%

别名:

2,2′-二吡啶基甲酮, 双(2-吡啶基)甲酮

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关于此项目

经验公式(希尔记法):
C11H8N2O
化学文摘社编号:
分子量:
184.19
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
243-067-3
Beilstein/REAXYS Number:
126598
MDL number:
Assay:
99%
Form:
solid
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InChI key

QPOWUYJWCJRLEE-UHFFFAOYSA-N

InChI

1S/C11H8N2O/c14-11(9-5-1-3-7-12-9)10-6-2-4-8-13-10/h1-8H

SMILES string

O=C(c1ccccn1)c2ccccn2

assay

99%

form

solid

Quality Level

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)

functional group

ketone

Application

di-2-吡啶基酮已被用于制备具有“星形”拓扑结构的异常 {Ni(II)(3)Ln(III)(μ-OR)(6)}(3+)络合物。其单阴离子形式已用于合成三角形 Ni(2)M(M = 镧系元素,Y)络合物

Biochem/physiol Actions

衍生自二-2-吡啶基酮的席夫碱配体在 SK-N-MC 神经上皮瘤(癌)细胞中表现出抗增殖活性

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gergely Szakacs et al.
FEBS letters, 594(23), 3965-3985 (2020-10-25)
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Maram T Basha et al.
Dalton transactions (Cambridge, England : 2003), 41(21), 6536-6548 (2012-03-01)
The iron coordination and biological chemistry of a series of heterocyclic dithiocarbazate Schiff base ligands is reported with regard to their activity as Fe chelators for the treatment of Fe overload and also cancer. The ligands are analogous to tridentate
Hana Jansová et al.
Current medicinal chemistry, 26(2), 288-301 (2017-09-22)
Heart is a particularly sensitive organ to iron overload and cardiomyopathy due to the excessive cardiac iron deposition causes most deaths in disorders such as beta-thalassemia major. Free or loosely bound iron ions readily cycle between ferrous and ferric states
Joanna Masternak et al.
Materials (Basel, Switzerland), 13(16) (2020-08-14)
The oncological use of cisplatin is hindered by its severe side effects and a very important resistance problem. To overcome these problems, scientists have attempted to design new generation transition-metal anticancer complexes. In this study, we present new complexes, ruthenium(II)
Anastasia N Georgopoulou et al.
Dalton transactions (Cambridge, England : 2003), 46(38), 12835-12844 (2017-09-19)
The reaction of mixtures of Fe(O

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