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130214

5-硝基吲哚啉

Name: 5-硝基吲哚啉
Brand: ALDRICH

97%

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关于此项目

经验公式（希尔记法）:

C₈H₈N₂O₂

化学文摘社编号:

32692-19-6

分子量:

164.16

NACRES:

NA.22

PubChem Substance ID:

24847951

UNSPSC Code:

12352100

EC Number:

251-158-4

MDL number:

MFCD00005709

Assay:

97%

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属性

assay

97%

mp

92-94 °C (lit.)

functional group

nitro

SMILES string

[O-][N+](=O)c1ccc2NCCc2c1

InChI

1S/C8H8N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-2,5,9H,3-4H2

InChI key

WJQWYAJTPPYORB-UHFFFAOYSA-N

说明

Application

5-Nitroindoline was used to prepare acetylated glucosylamines using the Suvorov procedure.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators.

Carmine Ostacolo et al.

Journal of medicinal chemistry, 63(1), 163-185 (2019-12-10)

Kv7 K+ channels represent attractive pharmacological targets for the treatment of different neurological disorders, including epilepsy. In this paper, 42 conformationally restricted analogues of the prototypical Kv7 activator retigabine have been synthesized and tested by electrophysiological patch-clamp experiments as Kv7

Substituted glucosylamines containing the indole nucleus.

Magnin AA, et al.

Tetrahedron, 25(18), 4543-4550 (1969)

全球贸易项目编号

货号	GTIN
130214-25G	04061832841502
130214-5G	04061832841519