131040
甲基反丁烯二酸
99%
别名:
甲基富马酸
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关于此项目
线性分子式:
HOOCCH=C(CH3)COOH
化学文摘社编号:
分子量:
130.10
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
207-859-2
Beilstein/REAXYS Number:
1722680
MDL number:
InChI key
HNEGQIOMVPPMNR-NSCUHMNNSA-N
InChI
1S/C5H6O4/c1-3(5(8)9)2-4(6)7/h2H,1H3,(H,6,7)(H,8,9)/b3-2+
SMILES string
C\C(=C/C(O)=O)C(O)=O
assay
99%
form
powder
mp
200-202 °C (lit.)
Quality Level
Application
- 来自生物质中康酸的可再生异戊二烯的工艺设计和经济学分析：详细介绍了橡胶工业中的关键化学物质异戊二烯的可持续生产方法，该异戊二烯来自源于生物质的中康酸，体现了其与绿色化学和材料科学的相关性（Lundberg et al., 2019）。
- 基于脂肪族连接子中康酸的新型Al-MOF的绿色合成： Al-MIL-68-Mes的结构、性质和原位结晶研究：利用可用于催化、气体储存和分离技术的中康酸考察了新型金属有机框架（MOF）的合成和性质（Reinsch et al., 2018)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Clinica chimica acta; international journal of clinical chemistry, 110(2-3), 187-203 (1981-03-05)
Two metabolites, 4-hydroxyisovaleric acid and mesaconic acid, have been identified and quantified in the urine of a patient with isovaleric acidemia. These compounds do not appear to have been reported previously as being components of human metabolism. In addition, large
G Leschziner et al.
Journal of neurology, 258(8), 1489-1493 (2011-03-03)
We report a case of a patient with a rapidly progressive dementing illness and gait disturbance, in whom initial screening demonstrated a high methylmalonic acid level only, suggestive of a functional vitamin B(12) deficiency. Despite B(12) replacement therapy, he continued
Darius Moharregh-Khiabani et al.
PloS one, 5(7), e11769-e11769 (2010-07-30)
Fumaric acid esters (FAE) are a group of compounds which are currently under investigation as an oral treatment for relapsing-remitting multiple sclerosis. One of the suggested modes of action is the potential of FAE to exert a neuroprotective effect. We
Nicolle H R Litjens et al.
European journal of immunology, 34(2), 565-575 (2004-02-10)
Psoriasis vulgaris, a type-1 cytokine-mediated chronic skin disease, can be treated successfully with fumaric acid esters (FAE). Beneficial effects of this medication coincided with decreased production of IFN-gamma. Since dendritic cells (DC) regulate the differentiation of T helper (Th) cells
Maria Khomyakova et al.
Science (New York, N.Y.), 331(6015), 334-337 (2011-01-22)
Access to novel ecological niches often requires adaptation of metabolic pathways to cope with new environments. For conversion to cellular building blocks, many substrates enter central carbon metabolism via acetyl-coenzyme A (acetyl-CoA). Until now, only two such pathways have been
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