13155
N6-苄基腺苷
≥99.0%
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关于此项目
经验公式（希尔记法）:
C17H19N5O4
化学文摘社编号:
分子量:
357.36
EC Number:
224-298-9
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
56815
MDL number:
InChI key
MRPKNNSABYPGBF-LSCFUAHRSA-N
InChI
1S/C17H19N5O4/c23-7-11-13(24)14(25)17(26-11)22-9-21-12-15(19-8-20-16(12)22)18-6-10-4-2-1-3-5-10/h1-5,8-9,11,13-14,17,23-25H,6-7H2,(H,18,19,20)/t11-,13-,14-,17-/m1/s1
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccccc4)ncnc23
assay
≥99.0%
form
powder
mp
184-186 °C
storage temp.
2-8°C
Quality Level
Gene Information
human ... ADORA3(140)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
B C Froehler et al.
Nucleic acids research, 11(22), 8031-8036 (1983-11-25)
Sterically hindered N6-dialkylformamidine protected deoxyadenosine is more stable to acidic depurination than N6-benzoyldeoxyadenosine and is potentially a valuable protecting group in the synthesis of deoxyoligonucleotides.
Karel Dolezal et al.
Bioorganic & medicinal chemistry, 15(11), 3737-3747 (2007-04-10)
Cytokinin activity of forty-eight 6-benzyladenosine derivatives at both the receptor and cellular levels as well as their anticancer properties were compared in various in vitro assays. The compounds were prepared by the condensation of 6-chloropurine riboside with corresponding substituted benzylamines
Petr Dolezel et al.
Toxicology in vitro : an international journal published in association with BIBRA, 24(8), 2079-2083 (2010-07-20)
Cytotoxicity of two halogen derivatives of N⁶-benzyladenosine (BAPR), N⁶-(3-iodobenzyl)-adenosine (I-BAPR) and 2-chloro-N⁶-(3-iodobenzyl)-adenosine (Cl-I-BAPR), was tested in human leukemia U937 cell line. Our results revealed that their cytotoxicity was surprisingly low. I-BAPR and also Cl-I-BAPR induced cell death with morphological and
R G Luiten et al.
Nucleic acids research, 11(22), 8073-8085 (1983-11-25)
From in vitro protein synthesis studies and nucleotide sequence analysis it has been deduced that, unlike the major coat proteins of the hitherto studied filamentous bacterial viruses Ff (M13, fd and f1), IKe and Pf1, the major coat protein of
P Mlejnek
Journal of cellular biochemistry, 83(4), 678-689 (2001-12-18)
As an extension of our recently published work (Mlejnek and Kuglík [2000] J. Cell. Biochem. 77:6-17), the role of caspases in N(6)-benzylaminopurine riboside (BAPR)-induced apotosis in HL-60 cells was evaluated in this study. Here, BAPR-induced apoptosis was accompanied by activation
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