Quality Level
assay
97%
form
liquid
refractive index
n20/D 1.396 (lit.)
density
0.795 g/mL at 25 °C (lit.)
functional group
amine, isonitrile
storage temp.
2-8°C
SMILES string
CCCC[N+]#[C-]
InChI
1S/C5H9N/c1-3-4-5-6-2/h3-5H2,1H3
InChI key
FSBLVBBRXSCOKU-UHFFFAOYSA-N
Application
用异氰酸丁酯研究了从 生氢一氧化碳嗜热菌中分离得到的一氧化碳脱氢酶-II的晶体结构 。本研究的目的是探讨 NO 激活血蛋白可溶性鸟苷酸环化酶的机制 。
Biochem/physiol Actions
丁基异腈与细胞色素 P450 中血红素的三价铁和二价铁形成络合物 。
Other Notes
可能形成浑浊和/或沉淀,对纯度无影响。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
69.8 °F - closed cup
flash_point_c
21 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
Straight-chain alkyl isocyanides open the distal histidine gate in crystal structures of myoglobin .
Robert D Smith et al.
Biochemistry, 49(24), 4977-4986 (2010-05-21)
Crystal structures of methyl, ethyl, propyl, and butyl isocyanide bound to sperm whale myoglobin (Mb) reveal two major conformations. In the in conformer, His(E7) is in a "closed" position, forcing the ligand alkyl chain to point inward. In the out
Alessandra Pesce et al.
Methods in enzymology, 436, 303-315 (2008-02-02)
Protein matrix cavities and extended tunnels can effectively channel substrates and products to and from active sites in enzymes. Substrate and product channeling can enhance catalytic efficiency by reducing the intramolecular diffusion times to and from reaction centers. Moreover, protected
Y Imai et al.
Biochimica et biophysica acta, 1207(1), 49-57 (1994-07-20)
Thr-303 to Lys-mutated P-450 2E1, as well as Thr-301 to Lys-mutated P-450 2C2, had absorption spectra characteristic of a nitrogenous ligand-bound form of P-450, such as the pyridine complex of P-450 2E1; (i) in the ferric state, the red-shifted Soret
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 133280-5G | 04061836825195 |
| 133280-1G | 04061838729408 |

