133361
2-萘磺酰氯
99%
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关于此项目
经验公式（希尔记法）:
C10H7ClO2S
化学文摘社编号:
分子量:
226.68
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-219-9
Beilstein/REAXYS Number:
641898
MDL number:
Assay:
99%
Form:
solid
InChI key
OPECTNGATDYLSS-UHFFFAOYSA-N
InChI
1S/C10H7ClO2S/c11-14(12,13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H
SMILES string
ClS(=O)(=O)c1ccc2ccccc2c1
assay
99%
form
solid
bp
147.7 °C/0.6 mmHg (lit.)
mp
74-76 °C (lit.)
Quality Level
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Application
2-Naphthalenesulfonyl chloride was employed as capping reagent for primary amine to convert histamine to a selective histamine H3-receptor antagonist. It was used for pre-column derivatization during the high-performance liquid chromatographic assay of neomycin sulfate.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
M J Tozer et al.
Bioorganic & medicinal chemistry letters, 9(13), 1825-1830 (1999-07-16)
Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride. Higher receptor affinity and lower variability in the data from the various bioassays were achieved with the 2-naphthalensulfonamides of histamine homologues.
K Tsuji et al.
Journal of chromatography, 333(2), 365-380 (1985-10-04)
A normal-phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of spectinomycin hydrochloride and spectinomycin sulfate for detection at 254 nm. The method involves pre-column derivatization of secondary amines of spectinomycin with 2-naphthalenesulfonyl chloride (NSCl) using a
K Tsuji et al.
Journal of chromatography, 369(1), 105-115 (1986-11-07)
A normal phase high-performance liquid chromatographic (HPLC) method has been developed for the assay of neomycin sulfate. The method involves pre-column derivatization with 2-naphthalenesulfonyl chloride (NSCl) followed by extraction in chloroform and chromatography using a normal phase silica column with
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