Quality Level
assay
98%
form
solid
optical activity
[α]21/D −41°, c = 5 in 1 M HCl
bp
255 °C (lit.)
mp
37-39 °C (lit.)
density
1.124 g/mL at 25 °C (lit.)
functional group
amine, hydroxyl, phenyl
storage temp.
2-8°C
SMILES string
CN[C@@H](C)[C@H](O)c1ccccc1
InChI
1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m0/s1
InChI key
KWGRBVOPPLSCSI-WPRPVWTQSA-N
General description
(1R,2S)-(-)-Ephedrine, a chiral β-amino alcohol, is commonly used as a chiral auxiliary in asymmetric synthesis. It undergoes reduction to form (+)-methamphetamine.
Application
通用手性合成子,用于催化以及制备光学纯亚砜和噁唑烷。
(1R,2S)-(-)-Ephedrine can be used in the preparation of optically active phosphine-phosphonite ligands and chirally-substituted cyclopentadienyl (Cp) ligands. It reacts with phosphorus trichloride to form (2R,4S,5R)-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine. It can also act as a chiral resolving agent for (±)-mandelic acid.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
186.8 °F - closed cup
flash_point_c
86 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
A novel nucleoside phosphoramidite synthon derived from 1R, 2S-ephedrine
Iyer RP, et al
Tetrahedron Asymmetry, 6(5), 1051-1054 (1995)
A L Carey et al.
Diabetologia, 56(1), 147-155 (2012-10-16)
Brown adipose tissue (BAT) activation increases energy consumption and may help in the treatment of obesity. Cold exposure is the main physiological stimulus for BAT thermogenesis and the sympathetic nervous system, which innervates BAT, is essential in this process. However
A novel chiral cyclopentadienyl ligand based on ephedrine
van der Zeijden AAH
Tetrahedron Asymmetry, 6(4), 913-918 (1995)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 134910-100G | 04061838134769 |
| 134910-25G | 04061838730367 |

