135933
5-氯-2-羟基吡啶
97%
别名:
5-氯-2-吡啶醇
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关于此项目
经验公式（希尔记法）:
C5H4ClNO
化学文摘社编号:
分子量:
129.54
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
224-146-1
MDL number:
Assay:
97%
InChI key
SZFUWUOHDRMCKD-UHFFFAOYSA-N
InChI
1S/C5H4ClNO/c6-4-1-2-5(8)7-3-4/h1-3H,(H,7,8)
SMILES string
Oc1ccc(Cl)cn1
assay
97%
mp
163-165 °C (lit.)
functional group
chloro
Application
用 5-氯-2-羟基吡啶 (5-chloro-2-pyridinol) 研究双香豆素对黄嘌呤脱氢酶的影响 及黄嘌呤脱氢酶还原丝裂霉素 C 的机理 。
General description
5-氯-2-羟基吡啶作为供体配体，以两性离子形式存在，即 5-氯吡啶-2-酸酯存在于铜配合物中 。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
D L Gustafson et al.
Cancer research, 52(24), 6936-6939 (1992-12-15)
These studies examined the effect of dicumarol on xanthine dehydrogenase (XDH), an enzyme recently shown to bioreduce mitomycin C. Dicumarol, which has previously been shown to inhibit xanthine oxidase (XO), inhibited both XDH and XO mediated conversion of xanthine to
D L Gustafson et al.
Cancer research, 53(22), 5470-5474 (1993-11-15)
These studies examined the kinetic and mechanistic parameters of mitomycin C (MMC) bioreduction by xanthine dehydrogenase (XDH), an enzyme recently shown to be capable of MMC activation. The bioreduction of MMC by XDH leads to the formation of 2,7-diaminomitosene (2,7-DM)
Ji-Xin Yuan et al.
Acta crystallographica. Section C, Crystal structure communications, 58(Pt 4), M270-M272 (2002-04-05)
In the title compound, [Cu(C(5)H(4)ClNO)(2)(C(4)H(4)N(2))(H(2)O)(2)](ClO(4))(2), the Cu atom, which lies on an inversion centre, has an octahedral environment. The pyrazine ligand also lies about an inversion centre and links adjacent Cu atoms into a chain running along the b axis;
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