方案
99%
mp
125-128 °C (lit.)
SMILES字符串
Nc1cccc2cnccc12
InChI
1S/C9H8N2/c10-9-3-1-2-7-6-11-5-4-8(7)9/h1-6H,10H2
InChI key
DTVYNUOOZIKEEX-UHFFFAOYSA-N
一般描述
5-Aminoisoquinoline forms 1:1 host−guest inclusion complex with β-cyclodextrin. It enhances the chemiluminescence of luminol-H2O2-horseradish peroxidase.
应用
5-Aminoisoquinoline (5AIQ) was used to study the effect of addition of β-cyclodextrin on the absorption and emission properties of 5AIQ.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Relation between the structure of some heterocyclic derivatives and other compounds, and their effects as enhancers or inhibitors of the luminol-H2O2-horseradish peroxidase chemiluminescence.
Garcia SF, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 105(!), 11-14 (1997)
Host-guest complexation between 5-aminoisoquinoline and ?-cyclodextrin and its effect on spectral and prototropic characteristics.
Rajamohan R, et al.
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 73(1-4), 99-108 (2012)
Jürgen Bosch et al.
Journal of medicinal chemistry, 49(20), 5939-5946 (2006-09-29)
The 1.8 A resolution de novo structure of nucleoside 2-deoxyribosyltransferase (EC 2.4.2.6) from Trypanosoma brucei (TbNDRT) has been determined by SADa phasing in an unliganded state and several ligand-bound states. This enzyme is important in the salvage pathway of nucleoside
Sheikh Fayaz Ahmad et al.
Molecular immunology, 63(2), 394-405 (2014-10-12)
Increasing indication is unveiling a role for poly(ADP-ribose) polymerase (PARP)-1 in the regulation of inflammatory/immune responses. The aim of the present study was to determine the potential anti-inflammatory effects of PARP-1 inhibitor 5-aminoisoquinolinone (5-AIQ) to explore the role of PARP-1
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