Merck
CN
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文件

安全信息

13815

Sigma-Aldrich

1-苄基哌嗪

≥97.0% (GC)

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经验公式（希尔记法）:
C11H16N2
CAS号:
2759-28-6
分子量:
176.26
Beilstein:
141624
EC 号:
220-423-6
MDL编号:
MFCD00005967
PubChem化学物质编号:
57647104

质量水平

100

检测方案

≥97.0% (GC)

药品控制

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

折射率

n20/D 1.547 (lit.)
n20/D 1.547

mp

17-20 °C

密度

1.014 g/mL at 25 °C (lit.)

SMILES字符串

C1CN(CCN1)Cc2ccccc2

InChI

1S/C11H16N2/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13/h1-5,12H,6-10H2

InChI key

IQXXEPZFOOTTBA-UHFFFAOYSA-N

基因信息

rat ... Htr2a(29595) , Htr2c(25187)

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相关类别

一般描述

1-Benzylpiperazine has stimulant and euphoric properties. It is commonly used constituent of party pill drugs. It is a potential antidepressant and is an active metabolite of the withdrawn antidepressant drug piberaline.

应用

1-Benzylpiperazine was used to study the inhibition of various acetylcholinesterases by 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin and related compounds.

其他说明

可能实行销售限制

象形图

Corrosion
GHS05

警示用语：

Danger

危险声明

H314 - H412

危险分类

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

闪点(°F)

253.4 °F - closed cup

闪点(°C)

123 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

监管及禁止进口产品

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Simon Elliott et al.
Journal of analytical toxicology, 32(2), 172-177 (2008-03-13)
Piperazines such as 1-benzylpiperazine (BZP), 1-(3-trifluromethylphenyl)piperazine (3-TFMPP), and 1-(3-chlorophenyl)piperazine (3-CPP) have become recent drugs of abuse. With stimulant effects comparable to amphetamines but with a lower potency and differential global scheduling status, they have been sold as a supposed legal
Márcia Sá Monteiro et al.
Archives of toxicology, 87(6), 929-947 (2013-05-21)
N-benzylpiperazine (BZP) has become popular among recreational drug users as the major active ingredient of "party pills" due to its stimulant and euphoric properties. Before BZP legal restrictions, these pills were sold as a safe and legal alternative to classical
Paul Gee et al.
Clinical toxicology (Philadelphia, Pa.), 48(3), 230-233 (2010-02-27)
1-benzylpiperazine (BZP) is synthetic stimulant. It was legal and openly sold in New Zealand before October 1, 2008. Two cases of life-threatening toxicity associated with BZP use are reported in detail in this article. Case one describes an adult female
The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action.
Harel M, et al.
Molecular Pharmaceutics, 67(6), 1874-1881 (2005)
David M Wood et al.
Therapeutic drug monitoring, 34(4), 363-367 (2012-06-08)
Since the turn of the 21st century, there has been an increase in the availability and use of novel psychoactive substances (also known as "legal highs") across Europe. Currently, there is limited information available on the potential acute toxicity (harms)
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