质量水平
方案
99%
表单
solid
沸点
234 °C (lit.)
mp
36-39 °C (lit.)
官能团
carboxylic acid
SMILES字符串
CC1(CCCCC1)C(O)=O
InChI
1S/C8H14O2/c1-8(7(9)10)5-3-2-4-6-8/h2-6H2,1H3,(H,9,10)
InChI key
REHQLKUNRPCYEW-UHFFFAOYSA-N
一般描述
1-Methyl-1-cyclohexanecarboxylic acid is the structural analog of valproic acid and its pharmacokinetic action has been studied in female Sprague-Dawley rats.
应用
1-Methyl-1-cyclohexanecarboxylic acid was used as internal standard during the determination of valproic acid metabolites.
生化/生理作用
1-Methyl-1-cyclohexanecarboxylic acid is an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
213.8 °F - closed cup
闪点(°C)
101.00 °C - closed cup
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
V P Poluianov
Sudebno-meditsinskaia ekspertiza, 35(1), 31-32 (1992-01-01)
Method of extraction-atomic absorption detection of arsenic in biologic material using naphthenic acid was developed and tested. Method can be used for arsenic detection in postmortem material. It differs from the known method by its accuracy, reliability and simple use.
Effects of 1-methyl cyclohexane carboxylic acid (CCA) on cellular energetics in neuroblastoma cells.
B Croizat et al.
Biochemical and biophysical research communications, 103(3), 1044-1051 (1981-12-15)
J L Vayssiere et al.
Biochemical and biophysical research communications, 140(3), 789-796 (1986-11-14)
CCA, a potent neuroblastoma differentiation inducer, was shown by oxygraphic measurements to reduce significantly the O2 consumption of whole neuroblastoma cells as of mitochondria purified from neuroblastoma or mouse cortex. The effect of CCA on the respiration was compared to
Effects on the cytoskeleton of a new inducer of the neuroblastoma morphological differentiation.
M M Portier et al.
Biochemical and biophysical research communications, 96(4), 1610-1618 (1980-10-31)
J L Vayssière et al.
Biochemical and biophysical research communications, 120(2), 411-419 (1984-04-30)
The evolution of three major mit-proteins was followed in neuroblastoma cells cultured in different conditions of differentiation. 1 methyl cyclohexane carboxylic acid (CCA) was found to stimulate the synthesis of the three mit-protein markers. This result, compared to the effects
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