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线性分子式:
[(CH3)3C]2C6H2(OH)CO2H
化学文摘社编号:
分子量:
250.33
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
215-823-2
Beilstein/REAXYS Number:
2216948
MDL number:
产品名称
3,5-二叔丁基-4-羟基苯甲酸, 98%
InChI key
YEXOWHQZWLCHHD-UHFFFAOYSA-N
InChI
1S/C15H22O3/c1-14(2,3)10-7-9(13(17)18)8-11(12(10)16)15(4,5)6/h7-8,16H,1-6H3,(H,17,18)
SMILES string
CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(O)=O
assay
98%
form
solid
mp
206-209 °C (lit.)
functional group
carboxylic acid
Quality Level
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Application
3,5-Di-tert-butyl-4-hydroxybenzoic acid was used in the synthesis of antistress agents.
General description
3,5-Di-tert-butyl-4-hydroxybenzoic acid is a metabolite of butylated hydroxytoluene.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
H Verhagen et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 27(12), 765-772 (1989-12-01)
The kinetics and metabolism of butylated hydroxytoluene (BHT) in man and rats have been compared. Single oral doses of 200, 63 or 20 mg BHT/kg body weight were administered to rats and a single oral dose of 0.5 mg/kg body
Rosario Rodil et al.
Journal of chromatography. A, 1217(41), 6428-6435 (2010-09-08)
The development and performance evaluation of an analytical method dedicated to the comprehensive determination of the most relevant antioxidants and their metabolites in aqueous environmental samples is presented. This was achieved by a miniaturised solid-phase extraction (SPE) with 10mg Oasis
B Spinnewyn et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 19(2), 139-143 (1999-02-23)
Both nitric oxide synthase (NOS) inhibitors and free radical scavengers have been shown to protect brain tissue in ischemia-reperfusion injury. Nitric oxide and superoxide anion act via distinct mechanisms and react together to form the highly deleterious peroxynitrite. Therefore the
C Park et al.
Biochemistry, 35(36), 11895-11900 (1996-09-10)
Vitreoscilla cytochrome bo ubiquinol oxidase is similar in some properties to the Escherichia coli enzyme, but unlike the latter, the Vitreoscilla oxidase functions as a primary Na+ pump. When purified Vitreoscilla cytochrome bo is incorporated into liposomes made from Vitreoscilla
K Yamamoto et al.
Chemical & pharmaceutical bulletin, 39(2), 512-514 (1991-02-01)
The metabolic pathway of butylated hydroxytoluene (BHT) to the ring-oxygenated metabolites 2,6-di-tert-butylhydroquinone (BHQ) and 2,6-di-tert-butyl-p-benzoquinone (BBQ) was examined in rats. After intraperitoneal administration of 3,5-di-tert-butyl-4-hydroxybenzoic acid (BHT-acid), which had been regarded as one of the major metabolic end-products of BHT
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