143510
5-羟基吲哚-2-甲酸
≥96.5%
别名:
NSC 117338
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经验公式（希尔记法）:
C9H7NO3
化学文摘社编号:
分子量:
177.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
244-468-6
Beilstein/REAXYS Number:
153214
MDL number:
产品名称
5-羟基吲哚-2-甲酸, ≥96.5%
Quality Level
InChI key
BIMHWDJKNOMNLD-UHFFFAOYSA-N
InChI
1S/C9H7NO3/c11-6-1-2-7-5(3-6)4-8(10-7)9(12)13/h1-4,10-11H,(H,12,13)
SMILES string
Oc1ccc2[nH]c(cc2c1)C(O)=O
assay
≥96.5%
form
powder
mp
249 °C (dec.) (lit.)
solubility
chloroform/ethanol (1:1): soluble 50 mg/mL, clear to slightly hazy, yellow to brown
functional group
carboxylic acid
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Application
5-羟吲哚-2-羧酸用于血浆、血小板和尿液中血清素的HPLC-安培检测。
- 吲哚 C5-O-取代开环-环丙基吲哚类化合物的合成及其抗癌活性
- 微波组合合成 5-HT1A、5-HT2A 和 5-HT2C 受体配体吲哚芳基哌嗪衍生物的反应物
- 制备新型天然辐射防护剂黑色素的反应物
- 5-羟吲哚-2-羧酸酰胺类组胺-3 受体反向激动剂的合成
- 用于制备构象约束的信号转导和转录激活因子 3 (Stat3) 的类肽抑制剂的反应物
- 用于制备恶二唑类似物的反应物，作为酪氨酸激酶 ZAP-70 的非肽类 SH2 抑制剂
General description
用KMnO 4氧化5-羟基吲哚-2-羧酸，生成吡咯-2,3,5-三羧酸。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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