Quality Level
assay
99%
form
solid
bp
216-220 °C (lit.)
mp
127-131 °C (lit.)
density
1.013 g/mL at 25 °C (lit.)
functional group
amide
SMILES string
CC(C)C(N)=O
InChI
1S/C4H9NO/c1-3(2)4(5)6/h3H,1-2H3,(H2,5,6)
InChI key
WFKAJVHLWXSISD-UHFFFAOYSA-N
Application
异丁酰胺在合成过程中用于人血清白蛋白的化学接枝序列组装蛋白胶囊 。
Biochem/physiol Actions
异丁酰胺激活人 γ-珠蛋白基因和鼠胚胎 ε（y）-珠蛋白基因的转录 。它可用于治疗 β-地中海贫血和镰状细胞病 。
S P Perrine et al.
British journal of haematology, 88(3), 555-561 (1994-11-01)
Butyrate and other short-chain fatty acids stimulate fetal globin gene expression and have potential for ameliorating the beta globin disorders. Butyrate, however, is rapidly metabolized in vivo and reaches only micromolar concentrations in plasma. We report here that a branched-chain
S P Perrine et al.
Experientia, 49(2), 133-137 (1993-02-15)
The inherited beta-hemoglobinopathies (sickle cell disease and beta thalassemia) are the result of a mutation in the adult (beta) globin gene. The fetal globin chain, encoded by the gamma globin genes, can substitute for the mutated or defective beta globin
L Hemmingsen et al.
European journal of biochemistry, 241(2), 546-551 (1996-10-15)
The coordination geometry of the metal at the active site in Cd-substituted horse liver alcohol dehydrogenase (LADH) has been investigated for the binary complexes of LADH with imidazole, isobutyramide, decanoic acid and Cl-, and for the ternary complexes of LADH
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 144436-100G | 04061831828412 |
| 144436-25G | 04061838735645 |