14462
(−)-α-甜没药醇
≥93% (GC)
别名:
(-)-6-甲基-2-(4-甲基-3-环己烯-1-基)-5-庚烯-2-醇, 左美诺醇
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经验公式（希尔记法）:
C15H26O
化学文摘社编号:
分子量:
222.37
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
≥93% (GC)
旋光性
[α]/D -58±5°, neat
折射率
n20/D 1.496
官能团
hydroxyl
SMILES字符串
C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1
InChI
1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1
InChI key
RGZSQWQPBWRIAQ-CABCVRRESA-N
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一般描述
(-)-α-红没药醇是膜壳藻 Hymenocrater yazdianus 叶精油的主要成分。
应用
(-)-α-采用红没药醇 (Bisabolol) 对木香挥发油的杀利什曼病活性和细胞毒活性进行了研究。
生化/生理作用
α-红没药醇对原代急性白血病细胞有活性，包括 BCR-ABL (+) 急性淋巴细胞白血病 。它是大鼠气管平滑肌电压依赖性钙通道的抑制剂 。还可抑制人和大鼠胶质瘤细胞生长和存活 。是一种潜在的抗利什曼病的新型治疗药物 。
危险声明
预防措施声明
危险分类
Aquatic Chronic 3
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
289.4 °F - closed cup
闪点(°C)
143 °C - closed cup
个人防护装备
Eyeshields, Gloves
Shiva Masoudi et al.
Natural product communications, 7(1), 117-120 (2012-03-21)
Water-distilled essential oils from leaves of Hymenocrater yazdianus Rech.f., flowers of Stachys obtusicrena Boiss., and stems and flowers of Nepeta asterotricha Rech.f., which are endemic to Iran, were analyzed by GC and GC/MS. Fifty-five components of the leaf oil of
Aracélio Viana Colares et al.
Evidence-based complementary and alternative medicine : eCAM, 2013, 727042-727042 (2013-08-13)
The search for new immunopharmacological chemical agents to treat various diseases caused by bacteria, fungi, and protozoa, such as leishmaniasis, for example, has led to the exploration of potential products from plant species and their main active ingredients. Antimonial drugs
Seungbeom Kim et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(10), 2580-2585 (2011-07-21)
Although (-)-α-bisabolol, a natural monocyclic sesquiterpene alcohol, is often used as a cosmetic soothing supplement, little is known about its mechanisms of anti-inflammatory effects. Therefore, this study was designed to investigate anti-inflammatory effects of (-)-α-bisabolol and its mechanisms of action.
Takashi Seki et al.
Cancer science, 102(12), 2199-2205 (2011-09-03)
In the present study, we investigated whether α-bisabolol, a sesquiterpene alcohol present in essential oils derived from a variety of plants, has antitumor effects against pancreatic cancer. α-Bisabolol induced a decrease in cell proliferation and viability in pancreatic cancer cell
Nayrton Flávio Moura Rocha et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 44(4), 455-461 (2011-09-20)
This work examined the gastroprotection of (-)-α-bisabolol, an unsaturated optically active sesquiterpene alcohol obtained by the direct distillation essential oil from plants. (-)-α-Bisabolol has been described as a compound capable of reducing the gastric ulcer area in response to absolute
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