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经验公式(希尔记法):
C20H24N2O2
化学文摘社编号:
分子量:
324.42
UNSPSC Code:
12352104
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-003-2
Beilstein/REAXYS Number:
91867
MDL number:
产品名称
奎宁, 90%
InChI key
LOUPRKONTZGTKE-WZBLMQSHSA-N
InChI
1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
SMILES string
COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1
assay
90%
optical activity
[α]25/D −165°, c = 2 in ethanol
mp
173-175 °C (lit.)
functional group
hydroxyl
Quality Level
Gene Information
human ... ABCB1(5243), CYP2C9(1559), CYP2D6(1565)
rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)
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Application
在用薄层色谱法对从 木香 叶中获得的内生真菌的水乙醇提取物中的生物碱进行化学评价时,曾使用奎宁作为标准品。
羧酸的拆分剂。催化呋喃酮的动力学拆分。
Biochem/physiol Actions
钾通道阻断剂。
General description
奎宁是在金鸡纳树皮中发现的一种金鸡纳生物碱,因其抗疟疾属性而闻名。
Other Notes
剩余物为氢化奎宁
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
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