Quality Level
assay
90%
optical activity
[α]25/D −165°, c = 2 in ethanol
mp
173-175 °C (lit.)
functional group
hydroxyl
SMILES string
COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1
InChI
1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
InChI key
LOUPRKONTZGTKE-WZBLMQSHSA-N
Gene Information
human ... ABCB1(5243), CYP2C9(1559), CYP2D6(1565)
rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)
General description
奎宁是在金鸡纳树皮中发现的一种金鸡纳生物碱，因其抗疟疾属性而闻名。
Application
在用薄层色谱法对从 木香 叶中获得的内生真菌的水乙醇提取物中的生物碱进行化学评价时，曾使用奎宁作为标准品。
羧酸的拆分剂。催化呋喃酮的动力学拆分。
Biochem/physiol Actions
钾通道阻断剂。
Other Notes
剩余物为氢化奎宁
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1
存储类别
11 - Combustible Solids
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Chirality, 4, 323-323 (1992)
Chemical assessment and antimicrobial and antioxidant activities of endophytic fungi extracts isolated from Costus spiralis (Jacq.) Roscoe (Costaceae)
Marson Ascencio PG, et al
Evidence-Based Complementary and Alternative Medicine : ECAM, 2014 (2014)
Harald Noedl et al.
Antimicrobial agents and chemotherapy, 51(2), 651-656 (2006-11-23)
Azithromycin when used in combination with faster-acting antimalarials has proven efficacious in treating Plasmodium falciparum malaria in phase 2 clinical trials. The aim of this study was to establish optimal combination ratios for azithromycin in combination with either dihydroartemisinin or
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| G6171-100UL | 04061838031228 |
| G9269-1ML | 04061833650141 |
| G6171-200UL | 04061838031235 |
| G4546-100UG | 04061833631683 |
| G9269-.2ML | 04061833650134 |
| SAB2500462-100UG | 04061832483962 |
| 145904-50G | 04061835554232 |
| 145904-10G | 04061835554225 |