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Merck
CN

148776

3-羟基邻氨基苯甲酸

97%, for peptide synthesis

别名:

3-羟基邻氨基苯甲酸

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关于此项目

线性分子式:
HOC6H3(NH2)CO2H
化学文摘社编号:
分子量:
153.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
208-962-5
MDL number:
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产品名称

3-羟基邻氨基苯甲酸, 97%

InChI key

WJXSWCUQABXPFS-UHFFFAOYSA-N

InChI

1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)

SMILES string

Nc1c(O)cccc1C(O)=O

assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

240 °C (dec.) (lit.)

application(s)

peptide synthesis

Quality Level

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General description

3-羟基邻氨基苯甲酸是一种氨基苯甲酸,通常用作各种化学反应的中间体。

Application

<ul>
<li><strong>直接抑制酶以减轻喹啉酸的形成:</strong>用于在色氨酸分解代谢的犬尿氨酸途径中合成 2-氨基-3-羧基粘康酸半醛 (ACMS)(Sanz 等人,2022 年)。</li>
</ul>

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Guifang Gan et al.
Cell death discovery, 7(1), 173-173 (2021-07-08)
Sorafenib is the FDA-approved first-line target drug for HCC patients. However, sorafenib only confers 3-5 months of survival benefit with <30% of HCC patients. Thus, it is necessary to develop a sensitizer for hepatocellular carcinoma (HCC) to sorafenib. Here, we
NO scavenging by 3-hydroxyanthranilic acid and 3-hydroxykynurenine: N-nitrosation leads via oxadiazoles to o-quinone diazides
C Backhaus, et al.
Nitric Oxide, 19, 237-244 (2008)
Andrea Moglia et al.
Metabolic engineering, 12(3), 223-232 (2009-11-28)
Phenolic esters like chlorogenic acid play an important role in therapeutic properties of many plant extracts. We aimed to produce phenolic esters in baker's yeast, by expressing tobacco 4CL and globe artichoke HCT. Indeed yeast produced phenolic esters. However, the
F A Teulings et al.
Acta vitaminologica et enzymologica, 29(1-6), 108-112 (1975-01-01)
In comparison with healthy age- and sex-comparable subjects, a significantly higher concentration of unconjugated 3-hydroxyanthranilic acid was detected in the urine of untreated bladder and kidney carcinoma patients. Because of tryptophan metabolite 3-hydroxyanthranilic acid is suspected to be involved in
Lei Zhang et al.
European heart journal, 33(16), 2025-2034 (2012-06-20)
Cardiovascular disease is the most common cause of death in the world and atherosclerosis, an inflammatory process in the vessel wall, accounts for the majority of these deaths. The tryptophan metabolite 3-hydroxyanthranilic acid (3-HAA) has been shown to inhibit inflammation

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