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Merck
CN

149233

2,6-二甲基-2,5-庚二烯-4-酮

95%

别名:

佛尔酮, 对称-二异亚丙基丙酮

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线性分子式:
(CH3)2C=CHCOCH=C(CH3)2
化学文摘社编号:
分子量:
138.21
EC Number:
207-986-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1699751
MDL number:
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InChI key

MTZWHHIREPJPTG-UHFFFAOYSA-N

InChI

1S/C9H14O/c1-7(2)5-9(10)6-8(3)4/h5-6H,1-4H3

SMILES string

C\C(C)=C\C(=O)\C=C(\C)C

vapor density

4.8 (vs air)

vapor pressure

0.38 mmHg ( 20 °C), 1 mmHg ( 42 °C)

assay

95%

bp

198-199 °C (lit.)

mp

23-26 °C (lit.)

density

0.885 g/mL at 25 °C (lit.)

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

174.2 °F - closed cup

flash_point_c

79 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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Tom S Chan et al.
Biochemical and biophysical research communications, 317(1), 149-156 (2004-03-30)
Using isolated rat hepatocytes we have shown that glutathione (GSH) depletion by glutathione-S-transferase (GST)-catalyzed conjugation with 1-bromoheptane or phorone was accompanied by a significant elevation in ascorbate synthesis. Glycogenolysis was also stimulated without a significant rise in glucose synthesis. Furthermore
Sophie Cazanave et al.
Journal of hepatology, 46(5), 858-868 (2007-02-06)
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F Bahrami et al.
Chemico-biological interactions, 128(2), 97-113 (2000-10-12)
Previously we reported that methylsulphonyl-2,6-dichlorobenzene, 2, 6-(diCl-MeSO(2)-B), was irreversibly bound to the olfactory mucosa of mice and induced necrosis of the Bowman's glands with subsequent neuroepithelial degeneration and detachment. In this study, autoradiography and histopathology were used to determine tissue-localization
Tom S Chan et al.
Free radical biology & medicine, 38(7), 867-873 (2005-03-08)
Most animals synthesize ascorbate. It is an essential enzymatic cofactor for the synthesis of a variety of biological molecules and also a powerful antioxidant. There is, however, little direct evidence supporting an antioxidant role for endogenously produced ascorbate. Recently, we
H Hentze et al.
Hepatology (Baltimore, Md.), 30(1), 177-185 (1999-07-01)
Agonistic engagement of the cytokine receptor CD95 in mice leads to activation of hepatic caspases, followed by massive hepatocyte apoptosis, acute liver failure, and death. This mechanism of cell death is thought to be associated with several human liver disorders.

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