质量水平
方案
99%
表单
solid
mp
>300 °C (lit.)
λmax
380 nm
399 nm (2nd)
SMILES字符串
O=C1c2ccccc2Nc3ccccc13
InChI
1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)
InChI key
FZEYVTFCMJSGMP-UHFFFAOYSA-N
基因信息
human ... ABCB1(5243)
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应用
9 (10H)-吖啶酮（吖啶酮）用于 9,10-二氢-9-氧代吖啶-10-戊酸甲酯的制备 。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Giuseppe Manfroni et al.
Journal of medicinal chemistry, 52(10), 3354-3365 (2009-04-25)
We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral
Dadi Chen et al.
Biotechnology for biofuels, 13, 130-130 (2020-07-24)
Considerable interest has been expressed in the development of anaerobic digestion (AD) of straw to solve the environmental problems caused by the dumping and burning of straw and to generate clean energy. However, the poor biodegradability of straw and the
A novel acridone derivative for the fluorescence tagging and mass spectrometric sequencing of peptides.
Chemical Communications (Cambridge, England), 16, 1529-1530 (1997)
Richele P Severino et al.
Bioorganic & medicinal chemistry, 19(4), 1477-1481 (2011-02-01)
Cathepsin V is a lysosomal cysteine peptidase highly expressed in thymus, testis and corneal epithelium. Eleven acridone alkaloids were isolated from Swinglea glutinosa (Bl.) Merr. (Rutaceae), with eight of them being identified as potent and reversible inhibitors of cathepsin V
Florian Astelbauer et al.
Vector borne and zoonotic diseases (Larchmont, N.Y.), 11(7), 793-798 (2011-03-23)
Visceral and cutaneous leishmaniases are an important public health problem in endemic geographic regions in 88 countries worldwide, with around 12 million infected people. Treatment options are limited due to toxicity and teratogenicity of the available drugs, response problems in
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