150762
苯甲酰胺
zone-refined, purified by sublimation, 99.9%
别名:
苯甲酸酰胺
方案
99.9%
纯化方式
sublimation
mp
125-128 °C (lit.)
SMILES字符串
NC(=O)c1ccccc1
InChI
1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
InChI key
KXDAEFPNCMNJSK-UHFFFAOYSA-N
基因信息
human ... PARP1(142)
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生化/生理作用
抑制聚（ADP-核糖）聚合酶（PARP）。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Muta. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
356.0 °F - closed cup
闪点(°C)
180 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Jamin D Steffen et al.
Journal of medicinal chemistry, 54(15), 5403-5413 (2011-06-23)
The metabolism of poly(ADP-ribose) (PAR) in response to DNA strand breaks, which involves the concerted activities of poly(ADP-ribose) polymerases (PARPs) and poly(ADP-ribose) glycohydrolase (PARG), modulates cell recovery or cell death depending upon the level of DNA damage. While PARP inhibitors
M H Gschwend et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 831(1-2), 132-139 (2006-01-03)
The development of a validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) method with positive electrospray ionisation (ESI(+)) and multiple reaction monitoring (MRM) for the selective and sensitive bioanalytical determination of amisulpride, a substituted benzamide derivative, in human plasma is described. Plasma
A P de Jong et al.
Journal of chromatography, 419, 233-242 (1987-08-07)
A universal rapid, sensitive and selective high-performance liquid chromatographic method with UV detection at 230 nm has been developed for the determination of benzamide drugs in human plasma and urine. Sample pretreatment is carried out using solid-phase extraction columns, resulting
Ryoko Chiba et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 19(5), 785-789 (2003-05-29)
A column-switching high-performance liquid chromatographic method with fluorescence detection was developed for the simultaneous determination of four benzamide-type anti-psychotic drugs: sulpiride, tiapride, sultopride and metoclopramide in human serum. In this method, a TSKgel Super-ODS column was used as an analytical
J D Coyle et al.
Journal of pharmaceutical sciences, 76(5), 402-405 (1987-05-01)
We report a reversed-phase high-performance liquid chromatography method for the determination of procainamide (PA) and three of its metabolites, n-acetylprocainamide (NAPA), deethylprocainamide (DEPA), and deethyl-n-acetylprocainamide (DENAPA), in serum and urine. (p-Amino)-n-(2-dipropylaminoethyl)-benzamide was the internal standard. A phenyl column (1.0-mL/min flow
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