InChI key
KXDAEFPNCMNJSK-UHFFFAOYSA-N
InChI
1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
SMILES string
NC(=O)c1ccccc1
assay
99.9%
purified by
sublimation
Gene Information
human ... PARP1(142)
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Biochem/physiol Actions
抑制聚(ADP-核糖)聚合酶(PARP)。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Muta. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
356.0 °F - closed cup
flash_point_c
180 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Jamin D Steffen et al.
Journal of medicinal chemistry, 54(15), 5403-5413 (2011-06-23)
The metabolism of poly(ADP-ribose) (PAR) in response to DNA strand breaks, which involves the concerted activities of poly(ADP-ribose) polymerases (PARPs) and poly(ADP-ribose) glycohydrolase (PARG), modulates cell recovery or cell death depending upon the level of DNA damage. While PARP inhibitors
M H Gschwend et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 831(1-2), 132-139 (2006-01-03)
The development of a validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) method with positive electrospray ionisation (ESI(+)) and multiple reaction monitoring (MRM) for the selective and sensitive bioanalytical determination of amisulpride, a substituted benzamide derivative, in human plasma is described. Plasma
J D Coyle et al.
Journal of pharmaceutical sciences, 76(5), 402-405 (1987-05-01)
We report a reversed-phase high-performance liquid chromatography method for the determination of procainamide (PA) and three of its metabolites, n-acetylprocainamide (NAPA), deethylprocainamide (DEPA), and deethyl-n-acetylprocainamide (DENAPA), in serum and urine. (p-Amino)-n-(2-dipropylaminoethyl)-benzamide was the internal standard. A phenyl column (1.0-mL/min flow
Ryoko Chiba et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 19(5), 785-789 (2003-05-29)
A column-switching high-performance liquid chromatographic method with fluorescence detection was developed for the simultaneous determination of four benzamide-type anti-psychotic drugs: sulpiride, tiapride, sultopride and metoclopramide in human serum. In this method, a TSKgel Super-ODS column was used as an analytical
A P de Jong et al.
Journal of chromatography, 419, 233-242 (1987-08-07)
A universal rapid, sensitive and selective high-performance liquid chromatographic method with UV detection at 230 nm has been developed for the determination of benzamide drugs in human plasma and urine. Sample pretreatment is carried out using solid-phase extraction columns, resulting
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