Merck
CN

151882

Sigma-Aldrich

氧化氘

99.9 atom % D

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别名:
氘代水, 重水
经验公式(希尔记法):
D2O
CAS号:
分子量:
20.03
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.21

同位素纯度

99.9 atom % D

质量水平

形式

liquid

technique(s)

NMR: suitable
bio NMR: suitable

bp

101.4 °C (lit.)

mp

3.8 °C (lit.)

储存温度

room temp

SMILES string

[2H]O[2H]

InChI

1S/H2O/h1H2/i/hD2

InChI key

XLYOFNOQVPJJNP-ZSJDYOACSA-N

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相关类别

一般描述

氧化氘,一种氘代溶剂,是NMR(核磁共振)分析的标准固化溶剂。液态氧化氘的各种热力学性质(如分子间振动频率,氢键能,自由能,焓和熵)等都已得到了评估。D2O的电离常数(在5-50℃的范围内),pK值(在25℃)以及焓,熵,热容量变化(用于D2O的解离)都已被报道。

应用

在通过NMR的定量实验期间,氧化氘(重水,水-d2,D2O)已被用作溶剂用于溶解内部标准品和样品。它已用于溶解三(2,2′-联吡啶)二氯化钌(II)六水合物Ru(bpy)3.4
氧化氘还可用于:
  • 通过与三氟乙酸酐反应制备三氟乙酸-d。
  • 在钌催化剂存在下通过H/D交换反应作为伯醇和仲醇在β-碳位的氘代剂。
  • 与六甲基二硅烷一起作为钯转移试剂,用于炔烃在钯络合物存在下形成(E)-1,2-二氘代烯烃。

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储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How should I store Product 151882, Deuterium oxide, to preserve its purity?

    According to our MSDS, deuterium oxide is classified as hygroscopic and should be stored under an inert gas like nitrogen, to prevent hydrogenated water uptake.

  4. I don't have the ability to store Product 151882, Deuterium oxide, under nitrogen to prevent H2O uptake. Is there another way that I can work with D20 in order to preserve its purity?

    You may be interested in our ampulized deuterium oxide products: 521965 (10x0.6mL), 441376 (10x0.75mL) or 269794 (10x1mL). These products are ideal for one time use applications, like as an NMR solvent, because there is decreased chance of water uptake during storage.

  5. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Muidh Alheshibri et al.
Journal of colloid and interface science, 537, 123-131 (2018-11-14)
Robust methods for differentiating long-lived nanobubbles from other nanoparticles are required. Evaluation of the density and compressibility of nanoparticles should enable nanobubbles to be differentiated from other nanoparticles, although the response of nanobubbles to pressure can be strongly influenced by
Ruthenium-Catalyzed Regioselective Deuteration of Alcohols at the ?-Carbon Position with Deuterium Oxide.
Tse SKS, et al.
Chemistry?A European Journal , 17(49), 13918-13925 (2011)
Ling Rong Wong et al.
Biomedicines, 8(12) (2020-12-16)
Accumulating evidence suggests that disruptions in brain energy metabolism may be a key player in the pathogenesis of Alzheimer's disease (AD). Pioglitazone (PIO) has been found to exert beneficial effects on metabolic dysfunction in many AD preclinical studies. However, limited
Useful NMR solvent mixture for polyesters: Trifluoroacetic acid-d/chloroform-d.
Hariharan R and Pinkus AG.
Polym. Bull., 30(1), 91-95 (1993)
Yu-Hsi Lin et al.
Nature metabolism, 2(12), 1413-1426 (2020-11-25)
Inhibiting glycolysis remains an aspirational approach for the treatment of cancer. We have previously identified a subset of cancers harbouring homozygous deletion of the glycolytic enzyme enolase (ENO1) that have exceptional sensitivity to inhibition of its redundant paralogue, ENO2, through

商品

Use this reference table to find the coupling values and chemical shifts of our NMR (deuterated) solvents. Melting and boiling points, molecular weight, density, and CAS number are also listed.

相关内容

NMR spectroscopy elucidates molecular structure and purity via nuclear spin states in a strong magnetic field.

默克分享核磁共振波谱法是一种测定样本分子结构和化学成分的分析技术,主要分析自旋原子核和强磁场之间的相互作用。其工作原理是外加静磁场引起分子中的特定原子核选择性吸收射频,通过所吸收的能量诱导核自旋的跃迁并呈现在共振谱上。

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