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Merck
CN

15369

Sigma-Aldrich

N-Boc-乙二胺

≥98.0% (NT)

别名:

N-(2-氨乙基)氨基甲酸叔丁酯, N-Boc-1,2-二氨基乙烷

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关于此项目

线性分子式:
(CH3)3COCONHCH2CH2NH2
化学文摘社编号:
分子量:
160.21
Beilstein:
1932330
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

≥98.0% (NT)

反应适用性

reagent type: cross-linking reagent

折射率

n20/D 1.458 (lit.)
n20/D 1.458

沸点

72-80 °C/0.1 mmHg (lit.)

密度

1.012 g/mL at 20 °C (lit.)

官能团

Boc
amine

SMILES字符串

NCCNC(OC(C)(C)C)=O

InChI

1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10)

InChI key

AOCSUUGBCMTKJH-UHFFFAOYSA-N

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应用

  • Facile synthesis of new N-(aminocycloalkylene) amino acid compounds:描述N-Boc-乙二胺在2-{[2-(Boc-氨基)乙基]氨基}乙酸苄酯制备中的应用(G Matulevičiūtė et al., 2023)。
  • Synthesis of a new tripod BODIPY dye:报道N-Boc-乙二胺参与化学合成BODIPY染料(H Wang et al., 2022)。
  • Single‐Entity Electrocatalysis:讨论N-Boc-乙二胺在电催化用改性Co3O4纳米颗粒中的应用(T Quast et al., 2021)。

其他说明

乙二胺的单保护衍生物,制备药理活性类似物;引入乙二胺间隔基。

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis of N,N-dilactitol ethylenediamine: a versatile spacer for attachment of residualizing labels to protein.
M M Dowd et al.
Analytical biochemistry, 205(2), 369-371 (1992-09-01)
W S Saari et al.
Journal of medicinal chemistry, 34(10), 3132-3138 (1991-10-01)
Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl)benzene sulfonamide hydrochloride (11) proved to be preferentially toxic to hypoxic EMT6 mammary carcinoma cells. At 1 mM concentration in
E Morier-Teissier et al.
Journal of medicinal chemistry, 36(15), 2084-2090 (1993-07-23)
A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8-tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide Gly-Gly-His (GGH) has been synthesized. Such a molecule presents characteristics able to induce antitumor activity: compound
Hao Li et al.
Investigative ophthalmology & visual science, 58(12), 5142-5150 (2017-10-08)
Intravitreal injection of antiangiogenic agents is becoming a standard treatment for neovascular retinal diseases. Sustained release of therapeutics by injecting colloidal carriers is a promising approach to reduce the injection frequency, which reduces treatment burdens and the risk of complications
G. Kada et al.
Biochimica et Biophysica Acta, 1427, 33-33 (1998)

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