156965
环己甲酰氯
98%
别名:
六氢苯甲酰氯
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关于此项目
线性分子式:
C6H11COCl
化学文摘社编号:
分子量:
146.61
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-322-7
Beilstein/REAXYS Number:
742163
MDL number:
Assay:
98%
Form:
liquid
assay
98%
form
liquid
InChI key
RVOJTCZRIKWHDX-UHFFFAOYSA-N
InChI
1S/C7H11ClO/c8-7(9)6-4-2-1-3-5-6/h6H,1-5H2
SMILES string
ClC(=O)C1CCCCC1
Quality Level
bp
184 °C (lit.)
density
1.096 g/mL at 25 °C (lit.)
functional group
acyl chloride
General description
已有研究报道了环己烷碳酰氯在乙腈中的悬汞电极上的电化学还原反应。
Application
环己烷碳酰氯被用于制备具有抗菌和抗酵母活性的五种硫脲衍生物配体：
- N-(二乙基硫代氨甲酰基)环己甲酰胺
- N-(二-正-丙基硫代氨甲酰基)环己甲酰胺
- (di-n-丁基硫代氨甲酰基)环己甲酰胺
- N-(二苯基硫代氨甲酰基)环己甲酰胺
- N-(吗啉-4-硫代氨甲酰基)环己甲酰胺
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 1
flash_point_f
150.8 °F
flash_point_c
66 °C
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Electrochemical reduction of cyclohexanecarbonyl chloride at mercury cathodes in acetonitrile.
Urove GA and Peters DG.
Journal of the Electrochemical Society, 140(4), 932-935 (1993)
Hakan Arslan et al.
Molecules (Basel, Switzerland), 14(1), 519-527 (2009-01-27)
Five thiourea derivative ligands and their Ni(2+) and Cu(2+) complexes have been synthesized. The compounds were screened for their in vitro anti-bacterial activity using Gram-positive bacteria (two different standard strains of Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Streptococcus pyogenes, Bacillus
Shigeo Hayashi et al.
Journal of enzyme inhibition and medicinal chemistry, 29(6), 846-867 (2014-02-13)
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional NSAIDs exhibit serious side-effects such as gastrointestinal damage
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