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Merck
CN

156965

环己甲酰氯

98%

别名:

六氢苯甲酰氯

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线性分子式:
C6H11COCl
化学文摘社编号:
分子量:
146.61
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-322-7
Beilstein/REAXYS Number:
742163
MDL number:
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产品名称

环己甲酰氯, 98%

assay

98%

form

liquid

InChI key

RVOJTCZRIKWHDX-UHFFFAOYSA-N

InChI

1S/C7H11ClO/c8-7(9)6-4-2-1-3-5-6/h6H,1-5H2

SMILES string

ClC(=O)C1CCCCC1

refractive index

n20/D 1.469 (lit.)

bp

184 °C (lit.)

density

1.096 g/mL at 25 °C (lit.)

functional group

acyl chloride

Quality Level

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Application

环己烷碳酰氯被用于制备具有抗菌和抗酵母活性的五种硫脲衍生物配体:
  • N-(二乙基硫代氨甲酰基)环己甲酰胺
  • N-(二--丙基硫代氨甲酰基)环己甲酰胺
  • (di-n-丁基硫代氨甲酰基)环己甲酰胺
  • N-(二苯基硫代氨甲酰基)环己甲酰胺
  • N-(吗啉-4-硫代氨甲酰基)环己甲酰胺

General description

已有研究报道了环己烷碳酰氯在乙腈中的悬汞电极上的电化学还原反应。

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

150.8 °F

flash_point_c

66 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

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Hakan Arslan et al.
Molecules (Basel, Switzerland), 14(1), 519-527 (2009-01-27)
Five thiourea derivative ligands and their Ni(2+) and Cu(2+) complexes have been synthesized. The compounds were screened for their in vitro anti-bacterial activity using Gram-positive bacteria (two different standard strains of Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Streptococcus pyogenes, Bacillus
Electrochemical reduction of cyclohexanecarbonyl chloride at mercury cathodes in acetonitrile.
Urove GA and Peters DG.
Journal of the Electrochemical Society, 140(4), 932-935 (1993)
Shigeo Hayashi et al.
Journal of enzyme inhibition and medicinal chemistry, 29(6), 846-867 (2014-02-13)
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional NSAIDs exhibit serious side-effects such as gastrointestinal damage

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