158194
2,2′-二硫双(5-硝基吡啶)
96%
别名:
DTNP, 双(5-硝基-2-吡啶基)二硫化物
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关于此项目
经验公式（希尔记法）:
C10H6N4O4S2
化学文摘社编号:
分子量:
310.31
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
218-344-7
Beilstein/REAXYS Number:
305413
MDL number:
Assay:
96%
Form:
solid
Quality Level
assay
96%
form
solid
mp
155-157 °C (lit.)
functional group
disulfide, nitro
SMILES string
[O-][N+](=O)c1ccc(SSc2ccc(cn2)[N+]([O-])=O)nc1
InChI
1S/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6H
InChI key
ROUFCTKIILEETD-UHFFFAOYSA-N
General description
2,2'-二硫代双（5-硝基吡啶）是芳香族二硫化物。
Application
使用 2,2'-二硫代双（5-硝基吡啶）：
- 用半胱氨酸活化试剂研究 G 蛋白偶联受体的核磁共振波谱
- 在用于受保护的含硒代半胱氨酸的肽的去保护测定中
- 对半胱氨酸和硒代半胱氨酸侧链上的 p -甲氧基苄基和乙酰胺甲基进行脱保护
- 从半胱氨酸和硒代半胱氨酸侧链中去除 p -甲氧基苄基保护基
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Uncoupling and energy transfer inhibition of photophosphorylation by sulfhydryl reagents.
J V Moroney et al.
The Journal of biological chemistry, 255(14), 6670-6674 (1980-07-25)
Katharine M Harris et al.
Journal of peptide science : an official publication of the European Peptide Society, 13(2), 81-93 (2006-10-13)
We present here a simple method for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cysteine and selenocysteine. This method uses the highly elecrophilic, aromatic disulfides 2,2'-dithiobis(5-nitropyridine) (DTNP) and 2,2'-dithiodipyridine (DTP) dissolved in TFA to effect removal of
Effects of oxidants on membrane potential, K+ and Ca2+ currents of mouse pancreatic B-cells.
P Krippeit-Drews et al.
Advances in experimental medicine and biology, 426, 355-359 (1997-01-01)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 158194-1G | 04061825970103 |
| 158194-10G | 04061832544670 |