质量水平
方案
96%
表单
solid
mp
155-157 °C (lit.)
官能团
disulfide
nitro
SMILES字符串
[O-][N+](=O)c1ccc(SSc2ccc(cn2)[N+]([O-])=O)nc1
InChI
1S/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6H
InChI key
ROUFCTKIILEETD-UHFFFAOYSA-N
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一般描述
2,2'-二硫代双(5-硝基吡啶)是芳香族二硫化物。
应用
使用 2,2'-二硫代双(5-硝基吡啶):
- 用半胱氨酸活化试剂研究 G 蛋白偶联受体的核磁共振波谱
- 在用于受保护的含硒代半胱氨酸的肽的去保护测定中
- 对半胱氨酸和硒代半胱氨酸侧链上的 p -甲氧基苄基和乙酰胺甲基进行脱保护
- 从半胱氨酸和硒代半胱氨酸侧链中去除 p -甲氧基苄基保护基
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
M K Park et al.
Experimental physiology, 80(5), 835-842 (1995-09-01)
Ca(2+)-activated K+ currents (IK(Ca)) and voltage-dependent Ca(2+)-insensitive K+ currents (IK(V)) were recorded using the patch clamp technique to study the pulmonary (PASMC) and ear arterial smooth muscle cells (EASMC) of the rabbit and the possible regulatory mechanisms related to hypoxia.
G J Stephens et al.
Pflugers Archiv : European journal of physiology, 431(3), 435-442 (1996-01-01)
The effects of cysteine-modifying reagents on the gating of rat cloned Kv1.4 channels expressed in HEK-293 cells were examined using the whole-cell patch-clamp technique. Cells transfected with Kv1.4 expressed a rapidly inactivating K+ current with a mid-point of activation of
A Li et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 18(17), 6740-6747 (1998-08-26)
Functional modifications of neuronal P/Q-type voltage-dependent Ca2+ channels expressed in Xenopus oocytes by oxidation were examined electrophysiologically. Oxidation by external H2O2 enhanced the whole-oocyte currents through the Ca2+ channels composed of the alpha1A, alpha2/delta, and beta3 subunits at negative voltages
Leah S Cohen et al.
Biopolymers, 102(1), 16-29 (2013-07-31)
Structural analysis by NMR of G protein-coupled receptors (GPCRs) has proven to be extremely challenging. To reduce the number of peaks in the NMR spectra by segmentally labeling a GPCR, we have developed a Guided Reconstitution method that includes the
Effects of oxidants on membrane potential, K+ and Ca2+ currents of mouse pancreatic B-cells.
P Krippeit-Drews et al.
Advances in experimental medicine and biology, 426, 355-359 (1997-01-01)
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