质量水平
方案
98%
表单
solid
mp
156-158 °C (lit.)
官能团
carboxylic acid
SMILES字符串
OC(=O)c1ccc2ccccc2n1
InChI
1S/C10H7NO2/c12-10(13)9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H,12,13)
InChI key
LOAUVZALPPNFOQ-UHFFFAOYSA-N
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一般描述
喹啉酸也称为喹啉-2-羧酸。已报告微波辅助合成喹啉酸取代苯胺的方法。抑制丙酮酸盐的氧化,α-大鼠肝线粒体中的酮戊二酸、谷氨酸和柠檬酸。喹啉酸是色氨酸降解的代谢产物,抑制灌注肝脏中的糖异生。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Zhao-Qing Du et al.
Journal of Cancer, 11(15), 4614-4624 (2020-06-04)
Platelet-derived growth receptor α (PDGFRα) is a key factor in many pathophysiological processes. The expression level of PDGFRα is significantly elevated in the early stage of liver development and maintained at a lower level in adult normal livers. In this
R M Epand
Medical hypotheses, 9(2), 207-213 (1982-08-01)
Ergothioneine is believed not to be synthesized by man but it accumulates to high concentrations in some mammalian cells as a result of dietary intake. Ergothioneine is known to chelate divalent metal ions with high affinity. Other substances which are
S Fetzner et al.
Biological chemistry Hoppe-Seyler, 374(6), 363-376 (1993-06-01)
Serratia marcecens 2CC-1 utilizes quinaldic acid (quinoline 2-carboxylic acid) as sole source of carbon, nitrogen and energy. Growth of strain 2CC-1 on quinaldic acid as well as on nicotinic acid and hypoxanthine was inhibited completely by the molybdate antagonist tungstate
Mode of action of hypoglycemic agents. 3. Studies on 5-methoxy indole-2-carboxylic acid and quinaldic acid.
J Reed et al.
The Journal of biological chemistry, 245(20), 5297-5303 (1970-10-25)
Graham Smith et al.
Acta crystallographica. Section C, Crystal structure communications, 64(Pt 3), o180-o183 (2008-03-07)
The structures of the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with 8-hydroxyquinoline, 8-aminoquinoline and quinoline-2-carboxylic acid (quinaldic acid), namely anhydrous 8-hydroxyquinolinium 2-carboxy-4,5-dichlorobenzoate, C(9)H(8)NO(+) x C(8)H(3)Cl(2)O(4)(-), (I), 8-aminoquinolinium 2-carboxy-4,5-dichlorobenzoate, C(9)H(9)N(2)(+) x C(8)H(3)Cl(2)O(4)(-), (II), and the adduct hydrate 2-carboxyquinolinium 2-carboxy-4,5-dichlorobenzoate quinolinium-2-carboxylate monohydrate
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