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160660

喹哪啶酸

Name: 喹哪啶酸
Brand: ALDRICH

98%

别名:

2-喹啉羧酸

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关于此项目

经验公式（希尔记法）:

C₁₀H₇NO₂

化学文摘社编号:

93-10-7

分子量:

173.17

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24849884

EC Number:

202-218-3

Beilstein/REAXYS Number:

126322

MDL number:

MFCD00006752

Assay:

98%

Form:

solid

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属性

Quality Level

200

assay

98%

form

solid

mp

156-158 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc2ccccc2n1

InChI

1S/C10H7NO2/c12-10(13)9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H,12,13)

InChI key

LOAUVZALPPNFOQ-UHFFFAOYSA-N

说明

General description

喹啉酸也称为喹啉-2-羧酸。已报告微波辅助合成喹啉酸取代苯胺的方法。抑制丙酮酸盐的氧化，α-大鼠肝线粒体中的酮戊二酸、谷氨酸和柠檬酸。喹啉酸是色氨酸降解的代谢产物，抑制灌注肝脏中的糖异生。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Studies on the biosynthesis of thiostrepton: 4-(1-hydroxyethyl)quinoline-2-carboxylate as a free intermediate on the pathway to the quinaldic acid moiety.

N D Priestley et al.

Bioorganic & medicinal chemistry, 4(7), 1135-1147 (1996-07-01)

Specifically 13C-labeled quinoline-2-carboxylate derivatives were synthesized from quinoline and used to study the biosynthesis of thiostrepton in a strain of Streptomyces laurentii. 13C NMR analysis of thiostrepton recovered after feeding methyl (RS)-[11-13C]-4-(1-hydroxyethyl)quinoline-2-carboxylate or methyl [11-13C]-4-acetylquinoline-2-carboxylate showed conclusively that these compounds

Microwave-assisted synthesis of new substituted anilides of quinaldic acid.

Pavel Bobal et al.

Molecules (Basel, Switzerland), 17(2), 1292-1306 (2012-02-02)

In this study a one step method for the preparation of substituted anilides of quinoline-2-carboxylic acid was developed. This efficient innovative approach is based on the direct reaction of an acid or ester with substituted anilines using microwave irradiation. The

Quinolinate-induced cortical cholinergic damage: modulation by tryptophan metabolites.

K Jhamandas et al.

Brain research, 529(1-2), 185-191 (1990-10-08)

Certain products of tryptophan metabolism interact with excitatory amino acid receptors to produce or protect against excitotoxicity. In this study, the action of several tryptophan metabolites, yielded by the kynurenine pathway, on cortical cholinergic toxicity was evaluated following focal injection

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全球贸易项目编号

货号	GTIN
160660-10G	04061838346360
160660-2.5G	04061833464533